TY - JOUR
T1 - Multiple chemodectomas
T2 - Carotid body tumor masked by salivary gland uptake on I-123 MIBG scintigraphy
AU - Weissman, A. F.
AU - Gonzalez, C. E.
AU - Shapiro, B.
AU - Shulkin, B.
AU - Francis, I. R.
AU - Leach, K.
N1 - Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.
PY - 1994
Y1 - 1994
N2 - Chemodectomas resemble pheochromocytomas in that they are derived from neural crest tissue. Their distribution in the body may be quite different, however, as chemodectomas are more frequently found in the aortic and carotid bodies, while pheochromocytomas are most common in the adrenal medulla. The authors present a case of a patient with a known history of chemodectoma, imaged with I-123 MIBG to rule out recurrent disease. Images of the chest revealed a thoracic tumor representing recurrent periaortic tumor, but an additional carotid body tumor (which was later demonstrated by angiography) was masked by salivary gland uptake. In patients with chemodectomas, SPECT imaging of the neck may be necessary to distinguish normal salivary gland uptake from tumoral uptake of MIBG. In general, knowledge of the characteristics of the individual neural crest derived tumor is mandatory for maximal effectiveness of I-123 MIBG scintigraphy.
AB - Chemodectomas resemble pheochromocytomas in that they are derived from neural crest tissue. Their distribution in the body may be quite different, however, as chemodectomas are more frequently found in the aortic and carotid bodies, while pheochromocytomas are most common in the adrenal medulla. The authors present a case of a patient with a known history of chemodectoma, imaged with I-123 MIBG to rule out recurrent disease. Images of the chest revealed a thoracic tumor representing recurrent periaortic tumor, but an additional carotid body tumor (which was later demonstrated by angiography) was masked by salivary gland uptake. In patients with chemodectomas, SPECT imaging of the neck may be necessary to distinguish normal salivary gland uptake from tumoral uptake of MIBG. In general, knowledge of the characteristics of the individual neural crest derived tumor is mandatory for maximal effectiveness of I-123 MIBG scintigraphy.
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U2 - 10.1097/00003072-199406000-00013
DO - 10.1097/00003072-199406000-00013
M3 - Article
C2 - 8062474
AN - SCOPUS:0028221161
SN - 0363-9762
VL - 19
SP - 527
EP - 531
JO - Clinical nuclear medicine
JF - Clinical nuclear medicine
IS - 6
ER -