Multiple Endocrine Neoplasia: Spectrum of Abdominal Manifestations

Anthony Davila; Christine O. Menias; Kinan Alhalabi; Chandana Lall; Perry J. Pickhardt; Meghan Lubner; Khaled M. Elsayes

doi:10.2214/AJR.19.22542

Multiple Endocrine Neoplasia: Spectrum of Abdominal Manifestations

Anthony Davila, Christine O. Menias, Kinan Alhalabi, Chandana Lall, Perry J. Pickhardt, Meghan Lubner, Khaled M. Elsayes

Abdominal Imaging

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

OBJECTIVE. Multiple endocrine neoplasia (MEN) syndromes are autosomal-dominant genetic disorders that predispose two or more organs of the endocrine system to tumor development. Although the diagnosis relies on clinical and serologic findings, imaging provides critical information for surgical management with the ultimate goal of complete tumor resection. CONCLUSION. This article reviews abdominal neoplasms associated with the various subtypes of MEN syndromes, with a focus on clinical presentation and characteristic imaging features.

Original language	English (US)
Pages (from-to)	885-895
Number of pages	11
Journal	American Journal of Roentgenology
Volume	215
Issue number	4
DOIs	https://doi.org/10.2214/AJR.19.22542
State	Published - Oct 2020

Keywords

Gastrinoma
Insulinoma
Multiple endocrine neoplasia
Pancreatic endocrine tumor
Somatostatinoma
Zollinger-ellison syndrome

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.2214/AJR.19.22542

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title = "Multiple Endocrine Neoplasia: Spectrum of Abdominal Manifestations",

abstract = "OBJECTIVE. Multiple endocrine neoplasia (MEN) syndromes are autosomal-dominant genetic disorders that predispose two or more organs of the endocrine system to tumor development. Although the diagnosis relies on clinical and serologic findings, imaging provides critical information for surgical management with the ultimate goal of complete tumor resection. CONCLUSION. This article reviews abdominal neoplasms associated with the various subtypes of MEN syndromes, with a focus on clinical presentation and characteristic imaging features.",

keywords = "Gastrinoma, Insulinoma, Multiple endocrine neoplasia, Pancreatic endocrine tumor, Somatostatinoma, Zollinger-ellison syndrome",

author = "Anthony Davila and Menias, {Christine O.} and Kinan Alhalabi and Chandana Lall and Pickhardt, {Perry J.} and Meghan Lubner and Elsayes, {Khaled M.}",

year = "2020",

month = oct,

doi = "10.2214/AJR.19.22542",

language = "English (US)",

volume = "215",

pages = "885--895",

journal = "American Journal of Roentgenology",

issn = "0361-803X",

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}

TY - JOUR

T1 - Multiple Endocrine Neoplasia

T2 - Spectrum of Abdominal Manifestations

AU - Davila, Anthony

AU - Menias, Christine O.

AU - Alhalabi, Kinan

AU - Lall, Chandana

AU - Pickhardt, Perry J.

AU - Lubner, Meghan

AU - Elsayes, Khaled M.

PY - 2020/10

Y1 - 2020/10

N2 - OBJECTIVE. Multiple endocrine neoplasia (MEN) syndromes are autosomal-dominant genetic disorders that predispose two or more organs of the endocrine system to tumor development. Although the diagnosis relies on clinical and serologic findings, imaging provides critical information for surgical management with the ultimate goal of complete tumor resection. CONCLUSION. This article reviews abdominal neoplasms associated with the various subtypes of MEN syndromes, with a focus on clinical presentation and characteristic imaging features.

AB - OBJECTIVE. Multiple endocrine neoplasia (MEN) syndromes are autosomal-dominant genetic disorders that predispose two or more organs of the endocrine system to tumor development. Although the diagnosis relies on clinical and serologic findings, imaging provides critical information for surgical management with the ultimate goal of complete tumor resection. CONCLUSION. This article reviews abdominal neoplasms associated with the various subtypes of MEN syndromes, with a focus on clinical presentation and characteristic imaging features.

KW - Gastrinoma

KW - Insulinoma

KW - Multiple endocrine neoplasia

KW - Pancreatic endocrine tumor

KW - Somatostatinoma

KW - Zollinger-ellison syndrome

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DO - 10.2214/AJR.19.22542

M3 - Review article

C2 - 32755185

AN - SCOPUS:85091589145

SN - 0361-803X

VL - 215

SP - 885

EP - 895

JO - American Journal of Roentgenology

JF - American Journal of Roentgenology

IS - 4

ER -

Multiple Endocrine Neoplasia: Spectrum of Abdominal Manifestations

Abstract

Keywords

ASJC Scopus subject areas

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