TY - JOUR
T1 - Multisystem crisis in a patient with presumptive renal cell carcinoma
AU - Bilen, Mehmet A.
AU - Waguespack, Steven G.
AU - Tannir, Nizar M.
AU - Pravinkumar, S. Egbert
AU - Tamboli, Pheroze
AU - Tu, Shi Ming
PY - 2008
Y1 - 2008
N2 - We describe the case of a patient who presented with a kidney lesion, lymphadenopathy, and bone metastasis. He developed a tetrad of high fever, encephalopathy, labile blood pressure, and multiple organ system failure. Initially, he was diagnosed with metastatic renal cell carcinoma (RCC). His fevers and encephalopathy were compatible with a putative paraneoplastic syndrome. Eventually, he was found to have malignant pheochromocytoma. To our knowledge, this is the first reported case of a malignant pheochromocytoma with multisystem crisis. Because of its atypical presentation and unusual findings, a high index of suspicion is necessary for the timely diagnosis of this clinical entity. Prompt diagnosis and appropriate treatments could improve the performance status and quality of life of such patients.
AB - We describe the case of a patient who presented with a kidney lesion, lymphadenopathy, and bone metastasis. He developed a tetrad of high fever, encephalopathy, labile blood pressure, and multiple organ system failure. Initially, he was diagnosed with metastatic renal cell carcinoma (RCC). His fevers and encephalopathy were compatible with a putative paraneoplastic syndrome. Eventually, he was found to have malignant pheochromocytoma. To our knowledge, this is the first reported case of a malignant pheochromocytoma with multisystem crisis. Because of its atypical presentation and unusual findings, a high index of suspicion is necessary for the timely diagnosis of this clinical entity. Prompt diagnosis and appropriate treatments could improve the performance status and quality of life of such patients.
KW - Bone metastasis
KW - Encephalopathy
KW - Fever
KW - Lymphadenopathy
KW - Multi-organ failure
KW - Pheochromocytoma
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U2 - 10.3816/CGC.2008.n.021
DO - 10.3816/CGC.2008.n.021
M3 - Article
C2 - 18824438
AN - SCOPUS:58149184690
SN - 1558-7673
VL - 6
SP - 128
EP - 130
JO - Clinical Genitourinary Cancer
JF - Clinical Genitourinary Cancer
IS - 2
ER -