Myeloproliferative and "Overlap" Myelodysplastic/Myeloproliferative Neoplasms

Beenu Thakral; John Anastasi; Sa A. Wang

doi:10.1016/B978-0-323-47913-4.00017-3

Myeloproliferative and "Overlap" Myelodysplastic/Myeloproliferative Neoplasms

Beenu Thakral, John Anastasi, Sa A. Wang

Hematopathology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

3 Scopus citations

Abstract

This chapter covers the topics of myeloproliferative neoplasms, myelodysplastic/myeloproliferative neoplasm, and myeloid/lymphoid neoplasms associated with eosinophilia and rearrangements of PDGFRA, PDGFRB, or FGFR1 or with PCM1-JAK2. Disease entities are reviewed in accord with the 2016 revision of the World Health Organization (WHO) classification of hematopoietic neoplasms. Each topic is discussed for its definition, clinical presentations, morphologic features, ancillary testing, differential diagnosis, and a brief summary of treatment and prognosis. For each disease, there is a fact sheet to provide a quick review of the key points. A total of 41 figures are provided to illustrate the morphologic features of various entities. This updated version has incorporated new discoveries and understanding of molecular genetics of the diseases and their implications in diagnosis, classification, prognosis, and therapy.

Original language	English (US)
Title of host publication	Hematopathology
Subtitle of host publication	A Volume in the Series: Foundations in Diagnostic Pathology
Publisher	Elsevier Inc.
Pages	488-538.e4
ISBN (Electronic)	9780323512312
ISBN (Print)	9780323479134
DOIs	https://doi.org/10.1016/B978-0-323-47913-4.00017-3
State	Published - 2018

Keywords

Atypical chronic myeloid leukemia (aCML), BCR-ABL1 negative
Chronic eosinophilic leukemia, not otherwise specified (CEL, NOS)
Chronic myeloid leukemia (CML)
Chronic myelomonocytic leukemia (CMML)
Chronic neutrophilic leukemia (CNL)
Essential thrombocythemia (ET)
Idiopathic hypereosinophilic syndrome (HES)
Juvenile myelomonocytic leukemia (JMML)
MDS/MPN with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T)
MDS/MPN, unclassifiable
Myeloid/lymphoid neoplasms associated with eosinophilia and rearrangements of PDGFRA, PDGFRB, or FGFR1 or with PCM1-JAK2
Myeloproliferative neoplasm unclassifiable (MPN-U)
Myeloproliferative neoplasms (MPN)
Polycythemia vera (PV)
Primary myelofibrosis (PMF)

ASJC Scopus subject areas

General Medicine

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10.1016/B978-0-323-47913-4.00017-3

Cite this

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title = "Myeloproliferative and {"}Overlap{"} Myelodysplastic/Myeloproliferative Neoplasms",

abstract = "This chapter covers the topics of myeloproliferative neoplasms, myelodysplastic/myeloproliferative neoplasm, and myeloid/lymphoid neoplasms associated with eosinophilia and rearrangements of PDGFRA, PDGFRB, or FGFR1 or with PCM1-JAK2. Disease entities are reviewed in accord with the 2016 revision of the World Health Organization (WHO) classification of hematopoietic neoplasms. Each topic is discussed for its definition, clinical presentations, morphologic features, ancillary testing, differential diagnosis, and a brief summary of treatment and prognosis. For each disease, there is a fact sheet to provide a quick review of the key points. A total of 41 figures are provided to illustrate the morphologic features of various entities. This updated version has incorporated new discoveries and understanding of molecular genetics of the diseases and their implications in diagnosis, classification, prognosis, and therapy.",

keywords = "Atypical chronic myeloid leukemia (aCML), BCR-ABL1 negative, Chronic eosinophilic leukemia, not otherwise specified (CEL, NOS), Chronic myeloid leukemia (CML), Chronic myelomonocytic leukemia (CMML), Chronic neutrophilic leukemia (CNL), Essential thrombocythemia (ET), Idiopathic hypereosinophilic syndrome (HES), Juvenile myelomonocytic leukemia (JMML), MDS/MPN with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T), MDS/MPN, unclassifiable, Myeloid/lymphoid neoplasms associated with eosinophilia and rearrangements of PDGFRA, PDGFRB, or FGFR1 or with PCM1-JAK2, Myeloproliferative neoplasm unclassifiable (MPN-U), Myeloproliferative neoplasms (MPN), Polycythemia vera (PV), Primary myelofibrosis (PMF)",

author = "Beenu Thakral and John Anastasi and Wang, {Sa A.}",

year = "2018",

doi = "10.1016/B978-0-323-47913-4.00017-3",

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pages = "488--538.e4",

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T1 - Myeloproliferative and "Overlap" Myelodysplastic/Myeloproliferative Neoplasms

AU - Thakral, Beenu

AU - Anastasi, John

AU - Wang, Sa A.

PY - 2018

Y1 - 2018

N2 - This chapter covers the topics of myeloproliferative neoplasms, myelodysplastic/myeloproliferative neoplasm, and myeloid/lymphoid neoplasms associated with eosinophilia and rearrangements of PDGFRA, PDGFRB, or FGFR1 or with PCM1-JAK2. Disease entities are reviewed in accord with the 2016 revision of the World Health Organization (WHO) classification of hematopoietic neoplasms. Each topic is discussed for its definition, clinical presentations, morphologic features, ancillary testing, differential diagnosis, and a brief summary of treatment and prognosis. For each disease, there is a fact sheet to provide a quick review of the key points. A total of 41 figures are provided to illustrate the morphologic features of various entities. This updated version has incorporated new discoveries and understanding of molecular genetics of the diseases and their implications in diagnosis, classification, prognosis, and therapy.

AB - This chapter covers the topics of myeloproliferative neoplasms, myelodysplastic/myeloproliferative neoplasm, and myeloid/lymphoid neoplasms associated with eosinophilia and rearrangements of PDGFRA, PDGFRB, or FGFR1 or with PCM1-JAK2. Disease entities are reviewed in accord with the 2016 revision of the World Health Organization (WHO) classification of hematopoietic neoplasms. Each topic is discussed for its definition, clinical presentations, morphologic features, ancillary testing, differential diagnosis, and a brief summary of treatment and prognosis. For each disease, there is a fact sheet to provide a quick review of the key points. A total of 41 figures are provided to illustrate the morphologic features of various entities. This updated version has incorporated new discoveries and understanding of molecular genetics of the diseases and their implications in diagnosis, classification, prognosis, and therapy.

KW - Atypical chronic myeloid leukemia (aCML), BCR-ABL1 negative

KW - Chronic eosinophilic leukemia, not otherwise specified (CEL, NOS)

KW - Chronic myeloid leukemia (CML)

KW - Chronic myelomonocytic leukemia (CMML)

KW - Chronic neutrophilic leukemia (CNL)

KW - Essential thrombocythemia (ET)

KW - Idiopathic hypereosinophilic syndrome (HES)

KW - Juvenile myelomonocytic leukemia (JMML)

KW - MDS/MPN with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T)

KW - MDS/MPN, unclassifiable

KW - Myeloid/lymphoid neoplasms associated with eosinophilia and rearrangements of PDGFRA, PDGFRB, or FGFR1 or with PCM1-JAK2

KW - Myeloproliferative neoplasm unclassifiable (MPN-U)

KW - Myeloproliferative neoplasms (MPN)

KW - Polycythemia vera (PV)

KW - Primary myelofibrosis (PMF)

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SN - 9780323479134

SP - 488-538.e4

BT - Hematopathology

PB - Elsevier Inc.

ER -

Myeloproliferative and "Overlap" Myelodysplastic/Myeloproliferative Neoplasms

Abstract

Keywords

ASJC Scopus subject areas

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