Neurogenic tumours of the posterior mediastinum and differential diagnosis considerations

Michael A. den Bakker; Annikka Weissferdt

doi:10.1111/his.15045

Neurogenic tumours of the posterior mediastinum and differential diagnosis considerations

Michael A. den Bakker, Annikka Weissferdt

Pathology, Anatomical

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

The mediastinal compartment harbours vital organs and structures, including the heart, great vessels, major airways, and thymus. These structures are embedded in and associated with soft-tissue elements consisting of adipose and fibro-collagenous tissue in which soft-tissue tumours may develop. A detailed inventory of soft-tissue tumours that may be encountered in the mediastinum based on the WHO 2013 classification was published in 2015. In addition, several comprehensive reviews on mediastinal soft-tissue pathology are available, including reviews focusing specifically on a single tumour type. This review will focus on primary neurogenic and spindle cell tumours of the somatic soft tissue of the posterior mediastinum and provide a discussion of the pertinent differential diagnoses.

Original language	English (US)
Pages (from-to)	238-252
Number of pages	15
Journal	Histopathology
Volume	84
Issue number	1
DOIs	https://doi.org/10.1111/his.15045
State	Published - Jan 2024

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology

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10.1111/his.15045

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title = "Neurogenic tumours of the posterior mediastinum and differential diagnosis considerations",

abstract = "The mediastinal compartment harbours vital organs and structures, including the heart, great vessels, major airways, and thymus. These structures are embedded in and associated with soft-tissue elements consisting of adipose and fibro-collagenous tissue in which soft-tissue tumours may develop. A detailed inventory of soft-tissue tumours that may be encountered in the mediastinum based on the WHO 2013 classification was published in 2015. In addition, several comprehensive reviews on mediastinal soft-tissue pathology are available, including reviews focusing specifically on a single tumour type. This review will focus on primary neurogenic and spindle cell tumours of the somatic soft tissue of the posterior mediastinum and provide a discussion of the pertinent differential diagnoses.",

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AB - The mediastinal compartment harbours vital organs and structures, including the heart, great vessels, major airways, and thymus. These structures are embedded in and associated with soft-tissue elements consisting of adipose and fibro-collagenous tissue in which soft-tissue tumours may develop. A detailed inventory of soft-tissue tumours that may be encountered in the mediastinum based on the WHO 2013 classification was published in 2015. In addition, several comprehensive reviews on mediastinal soft-tissue pathology are available, including reviews focusing specifically on a single tumour type. This review will focus on primary neurogenic and spindle cell tumours of the somatic soft tissue of the posterior mediastinum and provide a discussion of the pertinent differential diagnoses.

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Neurogenic tumours of the posterior mediastinum and differential diagnosis considerations

Abstract

ASJC Scopus subject areas

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