Abstract
In this issue of Blood, Romange and colleagues describe 1-7F9, a human monoclonal antibody targeting KIRs onNKcells.1 This antibody activates NK cells by blocking the interaction between inhibitory KIRs and target cell HLA class I molecules. This effect is demonstrated by the authors in vitro and in a mouse model of AML.
Original language | English (US) |
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Pages (from-to) | 2567-2568 |
Number of pages | 2 |
Journal | Blood |
Volume | 114 |
Issue number | 13 |
DOIs |
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State | Published - 2009 |
ASJC Scopus subject areas
- Biochemistry
- Immunology
- Hematology
- Cell Biology