Abstract
In this review of the use of intensity-modulated radiation therapy (IMRT) for treating locally advanced non-small cell lung cancer, topics discussed include aspects of treatment simulation, planning, and delivery and dose constraints and dosimetric findings used to predict treatment-related toxicity. Studies of toxicity arising from inadvertent radiation exposure of the normal lung, esophagus, and heart are described. Numerous treatment plan comparisons have been undertaken to demonstrate the putative dosimetric advantages of IMRT over previous techniques; results from these studies and clinical trials with analyses of survival outcomes and toxicity after IMRT versus other radiation therapy techniques are reviewed and discussed.
Original language | English (US) |
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Title of host publication | Intensity-Modulated Radiation Therapy |
Subtitle of host publication | Clinical Evidence and Techniques |
Publisher | Springer Japan |
Pages | 249-260 |
Number of pages | 12 |
ISBN (Electronic) | 9784431554868 |
ISBN (Print) | 9784431554851 |
DOIs | |
State | Published - Jan 1 2015 |
Keywords
- IMRT
- Non-small cell lung cancer
ASJC Scopus subject areas
- General Medicine
- General Physics and Astronomy