Non-small cell lung cancer

Quynh Nhu Nguyen, Ritsuko Komaki, Daniel R. Gomez, Zhongxing Liao

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

In this review of the use of intensity-modulated radiation therapy (IMRT) for treating locally advanced non-small cell lung cancer, topics discussed include aspects of treatment simulation, planning, and delivery and dose constraints and dosimetric findings used to predict treatment-related toxicity. Studies of toxicity arising from inadvertent radiation exposure of the normal lung, esophagus, and heart are described. Numerous treatment plan comparisons have been undertaken to demonstrate the putative dosimetric advantages of IMRT over previous techniques; results from these studies and clinical trials with analyses of survival outcomes and toxicity after IMRT versus other radiation therapy techniques are reviewed and discussed.

Original languageEnglish (US)
Title of host publicationIntensity-Modulated Radiation Therapy
Subtitle of host publicationClinical Evidence and Techniques
PublisherSpringer Japan
Pages249-260
Number of pages12
ISBN (Electronic)9784431554868
ISBN (Print)9784431554851
DOIs
StatePublished - Jan 1 2015

Keywords

  • IMRT
  • Non-small cell lung cancer

ASJC Scopus subject areas

  • General Medicine
  • General Physics and Astronomy

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