Noninvasive mechanical ventilation in high-risk pulmonary infections: A clinical review

Antonio M. Esquinas, S. Egbert Pravinkumar, Raffaele Scala, Peter Gay, Arie Soroksky, Christophe Girault, Fang Han, David S. Hui, Peter J. Papadakos, Nicolino Ambrosino

Research output: Contribution to journalReview articlepeer-review

47 Scopus citations

Abstract

The aim of this article was to review the role of noninvasive ventilation (NIV) in acute pulmonary infectious diseases, such as severe acute respiratory syndrome (SARS), H1N1 and tuberculosis, and to assess the risk of disease transmission with the use of NIV from patients to healthcare workers.

We performed a clinical review by searching Medline and EMBASE. These databases were searched for articles on “clinical trials” and “randomised controlled trials”. The keywords selected were non-invasive ventilation pulmonary infections, influenza-A (H1N1), SARS and tuberculosis. These terms were crossreferenced with the following keywords: health care workers, airborne infections, complications, intensive care unit and pandemic. The members of the International NIV Network examined the major results regarding NIV applications and SARS, H1N1 and tuberculosis. Cross-referencing mechanical ventilation with SARS yielded 76 studies, of which 10 studies involved the use of NIV and five were ultimately selected for inclusion in this review. Cross-referencing with H1N1 yielded 275 studies, of which 27 involved NIV. Of these, 22 were selected for review. Cross-referencing with tuberculosis yielded 285 studies, of which 15 involved NIV and from these seven were selected. In total 34 studies were selected for this review.

NIV, when applied early in selected patients with SARS, H1N1 and acute pulmonary tuberculosis infections, can reverse respiratory failure. There are only a few reports of infectious disease transmission among healthcare workers.

Original languageEnglish (US)
Pages (from-to)427-438
Number of pages12
JournalEuropean Respiratory Review
Volume23
Issue number134
DOIs
StatePublished - Dec 1 2014

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Fingerprint

Dive into the research topics of 'Noninvasive mechanical ventilation in high-risk pulmonary infections: A clinical review'. Together they form a unique fingerprint.

Cite this