TY - JOUR
T1 - Oligonucleotide therapy for hematological malignancies
AU - Tari, Ana M.
AU - Lopez-Berestein, Gabriel
N1 - Funding Information:
This work was supported in part by a grant from RGene Pharmaceutics
PY - 1997
Y1 - 1997
N2 - We have studied the incorporation of various oligonucleotides (oligos) in liposomes. Some of these oligos are hydrophilic while others are lipophilic. Typically, the lipophilic oligos were incorporated at a higher efficiency than the hydrophilic oligos. Nonetheless, liposomes could increase the intracellular delivery of both of these types of oligos.
AB - We have studied the incorporation of various oligonucleotides (oligos) in liposomes. Some of these oligos are hydrophilic while others are lipophilic. Typically, the lipophilic oligos were incorporated at a higher efficiency than the hydrophilic oligos. Nonetheless, liposomes could increase the intracellular delivery of both of these types of oligos.
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U2 - 10.3109/08982109709035479
DO - 10.3109/08982109709035479
M3 - Article
AN - SCOPUS:0031054986
SN - 0898-2104
VL - 7
SP - 19
EP - 30
JO - Journal of Liposome Research
JF - Journal of Liposome Research
IS - 1
ER -