Oligonucleotide therapy for hematological malignancies

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6 Scopus citations


We have studied the incorporation of various oligonucleotides (oligos) in liposomes. Some of these oligos are hydrophilic while others are lipophilic. Typically, the lipophilic oligos were incorporated at a higher efficiency than the hydrophilic oligos. Nonetheless, liposomes could increase the intracellular delivery of both of these types of oligos.

Original languageEnglish (US)
Pages (from-to)19-30
Number of pages12
JournalJournal of Liposome Research
Issue number1
StatePublished - Jan 1 1997


ASJC Scopus subject areas

  • Pharmaceutical Science

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