TY - JOUR
T1 - Opioid use, misuse, and abuse
T2 - a narrative review about interventions to reduce opioid consumption and related adverse events in the perioperative setting
AU - Kim, Daniel D.
AU - Ramirez, Maria F.
AU - Cata, Juan P.
N1 - Publisher Copyright:
© 2021 EDIZIONI MINERVA MEDICA.
PY - 2022/4
Y1 - 2022/4
N2 - Opioids remain the most potent and predictable drug available for perioperative analgesia and moderate-to-severe cancer-related pain. However, their efficacy has been questioned in other clinical settings. Moreover, opioids are associated with a wide variety of dose-dependent adverse events, limiting their use. The indiscriminate prescription of opioids has fueled the so-called “opioid epidemic” in the United States and other developed countries. Thus, there has been a significant effort to develop strategies to curtail their unnecessary prescription. Here, we summarize the history, current trends, and new directions in perioperative opioid prescription in an unbiased manner.
AB - Opioids remain the most potent and predictable drug available for perioperative analgesia and moderate-to-severe cancer-related pain. However, their efficacy has been questioned in other clinical settings. Moreover, opioids are associated with a wide variety of dose-dependent adverse events, limiting their use. The indiscriminate prescription of opioids has fueled the so-called “opioid epidemic” in the United States and other developed countries. Thus, there has been a significant effort to develop strategies to curtail their unnecessary prescription. Here, we summarize the history, current trends, and new directions in perioperative opioid prescription in an unbiased manner.
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U2 - 10.23736/S0375-9393.21.15937-1
DO - 10.23736/S0375-9393.21.15937-1
M3 - Article
C2 - 34636223
AN - SCOPUS:85128488815
SN - 0375-9393
VL - 88
SP - 300
EP - 307
JO - Minerva Anestesiologica
JF - Minerva Anestesiologica
IS - 4
ER -