TY - JOUR
T1 - Oral premalignancy
T2 - New methods of detection and treatment
AU - Gillenwater, Ann
AU - Papadimitrakopoulou, Vali
AU - Richards-Kortum, Rebecca
PY - 2006/3
Y1 - 2006/3
N2 - Oral carcinogenesis proceeds through a stepwise accumulation of genetic damage over time. Because the oral cavity is easy to examine and risk factor for oral cancer are known, there is great opportunity to improve patient outcomes through diagnosis and treatment of premalignant lesions before the development of invasive oral carcinoma. This review provides a summary of developments in detection and diagnosis of oral premalignant lesions and innovative approaches to management of early oral neoplasia. These technological and therapeutic advances are much needed to improve the poor outcomes associated with oral cancer due to our inability to diagnose and treat this disease at an early, curable stage.
AB - Oral carcinogenesis proceeds through a stepwise accumulation of genetic damage over time. Because the oral cavity is easy to examine and risk factor for oral cancer are known, there is great opportunity to improve patient outcomes through diagnosis and treatment of premalignant lesions before the development of invasive oral carcinoma. This review provides a summary of developments in detection and diagnosis of oral premalignant lesions and innovative approaches to management of early oral neoplasia. These technological and therapeutic advances are much needed to improve the poor outcomes associated with oral cancer due to our inability to diagnose and treat this disease at an early, curable stage.
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U2 - 10.1007/s11912-006-0050-4
DO - 10.1007/s11912-006-0050-4
M3 - Review article
C2 - 16507225
AN - SCOPUS:33645542283
SN - 1523-3790
VL - 8
SP - 146
EP - 154
JO - Current oncology reports
JF - Current oncology reports
IS - 2
ER -