Abstract
Osteosarcoma primarily affects adolescents. The authors reviewed the records of eight patients aged 5 years or younger (of 470 patients with osteosarcoma) treated at their institution. Tumors (seven of high grade and one of low grade) arose mostly in the appendicular skeleton; one patient had metastases. One patient with low-grade osteosarcoma survived after surgery alone. Two with active disease died of chemotherapy toxicity. The remaining five (three received chemotherapy) underwent surgery and are long-term survivors. Two who underwent hemipelvectomy or hip disarticulation would likely have undergone limb-sparing surgery today. These findings and a review of the similar cases in the literature suggest that osteosarcoma's clinical characteristics are similar among young children and older children.
Original language | English (US) |
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Pages (from-to) | 43-47 |
Number of pages | 5 |
Journal | Journal of Pediatric Hematology/Oncology |
Volume | 28 |
Issue number | 1 |
State | Published - Jan 2006 |
Externally published | Yes |
Keywords
- Osteosarcoma
- Outcome
- Treatment
- Young children
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Hematology
- Oncology