Abstract
Introduction: We investigated outcomes and prognostic factors for patients treated for cutaneous angiosarcoma (CA). Methods: We conducted a retrospective review of patients treated for CA of the face and scalp from 1962 to 2019. All received definitive treatment with surgery, radiation (RT), or a combination (S-XRT). The Kaplan–Meier method was used to estimate outcomes. Multivariable analyses were conducted using the Cox proportional hazards model. Results: For the 143 patients evaluated median follow-up was 33 months. Five-year LC was 51% and worse in patients with tumors >5 cm, multifocal tumors, those treated pre-2000, and with single modality therapy (SMT). These remained associated with worse LC on multivariable analysis. The 5-year disease-specific survival (DSS) for the cohort was 56%. Tumor size >5 cm, non-scalp primary site, treatment pre-2000, and SMT were associated with worse DSS. Conclusion: Large or multifocal tumors are negative prognostic factors in patients with head and neck CA. S-XRT improved outcomes.
Original language | English (US) |
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Pages (from-to) | 1943-1951 |
Number of pages | 9 |
Journal | Head and Neck |
Volume | 45 |
Issue number | 8 |
DOIs | |
State | Published - Aug 2023 |
Keywords
- angiosarcoma
- radiation
- surgery
ASJC Scopus subject areas
- Otorhinolaryngology