Ovarian Cancer Genetics and Implications for Imaging and Therapy

Sherif B. Elsherif; Silvana C. Faria; Chandana Lall; Revathy Iyer; Priya R. Bhosale

doi:10.1097/RCT.0000000000000932

Ovarian Cancer Genetics and Implications for Imaging and Therapy

Sherif B. Elsherif, Silvana C. Faria, Chandana Lall, Revathy Iyer, Priya R. Bhosale

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Abstract

Ovarian cancer is the second most common gynecologic malignancy in the United States. Ovarian cancer has a dismal prognosis when diagnosed at an advanced stage. Therapy for these cancers is determined not only by stage but also by their heterogeneous pathologic features, genetic mutations, and biology. In this review, we will discuss types of epithelial ovarian cancer, and their associated genetic mutations and the implications for imaging and treatment.

Original language	English (US)
Pages (from-to)	835-845
Number of pages	11
Journal	Journal of computer assisted tomography
Volume	43
Issue number	6
DOIs	https://doi.org/10.1097/RCT.0000000000000932
State	Published - Nov 1 2019

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1097/RCT.0000000000000932

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abstract = "Ovarian cancer is the second most common gynecologic malignancy in the United States. Ovarian cancer has a dismal prognosis when diagnosed at an advanced stage. Therapy for these cancers is determined not only by stage but also by their heterogeneous pathologic features, genetic mutations, and biology. In this review, we will discuss types of epithelial ovarian cancer, and their associated genetic mutations and the implications for imaging and treatment.",

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AU - Elsherif, Sherif B.

AU - Faria, Silvana C.

AU - Lall, Chandana

AU - Iyer, Revathy

AU - Bhosale, Priya R.

PY - 2019/11/1

Y1 - 2019/11/1

N2 - Ovarian cancer is the second most common gynecologic malignancy in the United States. Ovarian cancer has a dismal prognosis when diagnosed at an advanced stage. Therapy for these cancers is determined not only by stage but also by their heterogeneous pathologic features, genetic mutations, and biology. In this review, we will discuss types of epithelial ovarian cancer, and their associated genetic mutations and the implications for imaging and treatment.

AB - Ovarian cancer is the second most common gynecologic malignancy in the United States. Ovarian cancer has a dismal prognosis when diagnosed at an advanced stage. Therapy for these cancers is determined not only by stage but also by their heterogeneous pathologic features, genetic mutations, and biology. In this review, we will discuss types of epithelial ovarian cancer, and their associated genetic mutations and the implications for imaging and treatment.

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Ovarian Cancer Genetics and Implications for Imaging and Therapy

Abstract

ASJC Scopus subject areas

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