Abstract
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune disorder of the central nervous system that commonly manifests as a complex neuropsychiatric syndrome. Antibodies against myelin oligodendrocyte glycoprotein (MOG) are associated with a range of clinical presentations including acute disseminated encephalomyelitis (ADEM), optic neuritis, and transverse myelitis. The concurrence of NMDAR encephalitis and demyelinating syndromes is rare. We describe the case of a 29-year-old male with NMDAR encephalitis and overlapping MOG antibody disease. The aim of this report is to add to the growing knowledge of phenotypic characteristics of overlap syndromes as their clinical and prognostic features may differ from those of single antibody disease.This manuscript requires color print.
Original language | English (US) |
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Article number | 577124 |
Journal | Journal of Neuroimmunology |
Volume | 339 |
DOIs | |
State | Published - Feb 15 2020 |
Keywords
- Autoimmune
- Encephalitis
- Myelin oligodendrocyte glycoprotein
- N-methyl-D-aspartate receptor
- Overlap syndrome
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Neurology
- Clinical Neurology