Abstract
A new classification of lung adenocarcinoma has been proposed recently-the International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification. Abundant information from recent lung cancer computed tomography (CT) screening programs has increased our understanding of the strong, although imperfect, correlation between histologic findings of lung adenocarcinoma and subsolid pulmonary nodules on CT, including both "pure" groundglass nodules (GGNs) and "part-solid" GGNs. Moreover, serial CT imaging has demonstrated stepwise progression of these nodules in a subset of patients, characterized by increase in size and density of GGNs and development of a solid component. Given the higher incidence of malignancy and the considerably lower growth rate of subsolid nodules, dedicated standardized guidelines for management of these nodules have been proposed, including long-term (≥ 3 y) CT follow-up using a low-dose technique. Radiologists should be familiar with the new terminology of lung adenocarcinomas and strategic management of subsolid pulmonary nodules.
Original language | English (US) |
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Pages (from-to) | 240-248 |
Number of pages | 9 |
Journal | Journal of Thoracic Imaging |
Volume | 27 |
Issue number | 4 |
DOIs | |
State | Published - Jul 2012 |
Keywords
- Adenocarcinoma
- Adenocarcinoma in situ
- Bronchioloalveolar cell carcinoma
- Ground-glass nodule
- Ground-glass opacities
- Lung Cancer
- Lung cancer screening
- Minimally invasive adenocarcinoma
- Multidetector computed tomography
- Pulmonary nodule
- Subsolid nodule
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Pulmonary and Respiratory Medicine