Pancreatic Malignancy (Non-adenocarcinoma)

Endoscopic ultrasound (EUS) is routinely employed in the evaluation of solid pancreatic masses as it enhances diagnostic accuracy, guides management, and improves patient outcomes. EUS is often performed to assist with preoperative localization of these tumors to help guide surgical resection, which offers the only chance for cure and is usually recommended due to the malignant potential of endocrine pancreatic tumors. Most tumors appear by EUS as a mildly hypoechoic, solid and less often cystic mass that may be single or multiple. It may be difficult to distinguish primary pancreatic masses from commonly accompanying prominent peripancreatic lymphadenopathy. Solid pseudopapillary tumors are rare pancreatic neoplasms that typically develop in young women in the second or third decade of life. Although acinar cells comprise over 80% of all pancreatic cells, acinar cell carcinoma accounts for less than 1% of all pancreatic neoplasms.