TY - JOUR
T1 - Perception of frailty in spinal metastatic disease
T2 - international survey of the AO Spine community
AU - The AO Spine Knowledge Forum Tumor
AU - MacLean, Mark A.
AU - Georgiopoulos, Miltiadis
AU - Charest-Morin, Raphaële
AU - Rory Goodwin, C.
AU - Laufer, Ilya
AU - Dea, Nicolas
AU - Shin, John H.
AU - Gokaslan, Ziya L.
AU - Rhines, Laurence D.
AU - O’Toole, John E.
AU - Sciubba, Daniel M.
AU - Fehlings, Michael G.
AU - Stephens, Byron F.
AU - Bettegowda, Chetan
AU - Myrehaug, Sten
AU - Disch, Alexander C.
AU - Netzer, Cordula
AU - Kumar, Naresh
AU - Sahgal, Arjun
AU - Germscheid, Niccole M.
AU - Weber, Michael H.
N1 - Publisher Copyright:
© 2023 The authors, CC BY-NC-ND 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/)
PY - 2023
Y1 - 2023
N2 - OBJECTIVE Frailty has not been clearly defined in the context of spinal metastatic disease (SMD). Given this, the objective of this study was to better understand how members of the international AO Spine community conceptualize, define, and assess frailty in SMD. METHODS The AO Spine Knowledge Forum Tumor conducted an international cross-sectional survey of the AO Spine community. The survey was developed using a modified Delphi technique and was designed to capture preoperative surrogate markers of frailty and relevant postoperative clinical outcomes in the context of SMD. Responses were ranked using weighted averages. Consensus was defined as ≥ 70% agreement among respondents. RESULTS Results were analyzed for 359 respondents, with an 87% completion rate. Study participants represented 71 countries. In the clinical setting, most respondents informally assess frailty and cognition in patients with SMD by forming a general perception based on clinical condition and patient history. Consensus was attained among respondents regarding the association between 14 preoperative clinical variables and frailty. Severe comorbidities, extensive systemic disease burden, and poor performance status were most associated with frailty.
AB - OBJECTIVE Frailty has not been clearly defined in the context of spinal metastatic disease (SMD). Given this, the objective of this study was to better understand how members of the international AO Spine community conceptualize, define, and assess frailty in SMD. METHODS The AO Spine Knowledge Forum Tumor conducted an international cross-sectional survey of the AO Spine community. The survey was developed using a modified Delphi technique and was designed to capture preoperative surrogate markers of frailty and relevant postoperative clinical outcomes in the context of SMD. Responses were ranked using weighted averages. Consensus was defined as ≥ 70% agreement among respondents. RESULTS Results were analyzed for 359 respondents, with an 87% completion rate. Study participants represented 71 countries. In the clinical setting, most respondents informally assess frailty and cognition in patients with SMD by forming a general perception based on clinical condition and patient history. Consensus was attained among respondents regarding the association between 14 preoperative clinical variables and frailty. Severe comorbidities, extensive systemic disease burden, and poor performance status were most associated with frailty.
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U2 - 10.3171/2023.1.SPINE221433
DO - 10.3171/2023.1.SPINE221433
M3 - Article
C2 - 36883617
AN - SCOPUS:85165439459
SN - 1547-5654
VL - 38
SP - 715
EP - 725
JO - Journal of Neurosurgery: Spine
JF - Journal of Neurosurgery: Spine
IS - 6
ER -