Peripheral blood stem cells for autografting

Elizabeth J. Shpall; Pablo J. Cagnoni; Scott I. Bearman; Maureen Ross; Roy B. Jones

doi:10.1146/annurev.med.48.1.241

Peripheral blood stem cells for autografting

Elizabeth J. Shpall, Pablo J. Cagnoni, Scott I. Bearman, Maureen Ross, Roy B. Jones

Stem Cell Transplantation

Research output: Contribution to journal › Review article › peer-review

14 Scopus citations

Abstract

High-dose therapy with autologous hematopoietic progenitor cell support is effective treatment for patients with a variety of high-risk malignancies. Accelerating of marrow recovery from near-lethal or lethal toxicity with hematopoietic cell support improves the safety and cost effectiveness of the high-dose regimens. Peripheral blood progenitor cells will soon replace marrow as the major source of hematopoietic support. This chapter reviews the techniques of peripheral blood progenitor cell collection, mobilization, purification (for tumor removal), and ex vivo expansion.

Original language	English (US)
Pages (from-to)	241-251
Number of pages	11
Journal	Annual Review of Medicine
Volume	48
DOIs	https://doi.org/10.1146/annurev.med.48.1.241
State	Published - 1997

Keywords

Autotransplants
Bone marrow
Peripheral blood progenitor cells

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1146/annurev.med.48.1.241

Cite this

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abstract = "High-dose therapy with autologous hematopoietic progenitor cell support is effective treatment for patients with a variety of high-risk malignancies. Accelerating of marrow recovery from near-lethal or lethal toxicity with hematopoietic cell support improves the safety and cost effectiveness of the high-dose regimens. Peripheral blood progenitor cells will soon replace marrow as the major source of hematopoietic support. This chapter reviews the techniques of peripheral blood progenitor cell collection, mobilization, purification (for tumor removal), and ex vivo expansion.",

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AU - Shpall, Elizabeth J.

AU - Cagnoni, Pablo J.

AU - Bearman, Scott I.

AU - Ross, Maureen

AU - Jones, Roy B.

PY - 1997

Y1 - 1997

N2 - High-dose therapy with autologous hematopoietic progenitor cell support is effective treatment for patients with a variety of high-risk malignancies. Accelerating of marrow recovery from near-lethal or lethal toxicity with hematopoietic cell support improves the safety and cost effectiveness of the high-dose regimens. Peripheral blood progenitor cells will soon replace marrow as the major source of hematopoietic support. This chapter reviews the techniques of peripheral blood progenitor cell collection, mobilization, purification (for tumor removal), and ex vivo expansion.

AB - High-dose therapy with autologous hematopoietic progenitor cell support is effective treatment for patients with a variety of high-risk malignancies. Accelerating of marrow recovery from near-lethal or lethal toxicity with hematopoietic cell support improves the safety and cost effectiveness of the high-dose regimens. Peripheral blood progenitor cells will soon replace marrow as the major source of hematopoietic support. This chapter reviews the techniques of peripheral blood progenitor cell collection, mobilization, purification (for tumor removal), and ex vivo expansion.

KW - Autotransplants

KW - Bone marrow

KW - Peripheral blood progenitor cells

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JO - Annual Review of Medicine

JF - Annual Review of Medicine

ER -

Peripheral blood stem cells for autografting

Abstract

Keywords

ASJC Scopus subject areas

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