Abstract
Twenty-six patients with metastatic breast cancer received cis-dichlorodiammineplatinum (II) either as a single dose of 100 mg/m 2 iv every 3-4 weeks or as a continuous 5-day infusion of 20 mg/m 2/day at 4-week intervals. Fourteen patients were treated with the single-dose schedule and 12 patients were treated with the continuous 5-day infusion. No significant response was observed with either dose schedule. Aside from a reduction in the frequency and severity of gastrointestinal toxicity with the continuous 5-day infusion, no real difference was seen with regard to renal and hematologic toxicity with either dose schedule.
Original language | English (US) |
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Pages (from-to) | 405-408 |
Number of pages | 4 |
Journal | Cancer Treatment Reports |
Volume | 62 |
Issue number | 3 |
State | Published - 1978 |
ASJC Scopus subject areas
- Oncology
- Cancer Research