TY - JOUR
T1 - Phenotypic Analysis of Preimplantation Mouse Embryos in Culture
AU - Papaioannou, Virginia E.
AU - Behringer, Richard R.
N1 - Publisher Copyright:
© 2023 Cold Spring Harbor Laboratory Press.
PY - 2023/12
Y1 - 2023/12
N2 - Preimplantation embryo culture is a valuable approach to investigate a preimplantation lethal phenotype. Standard culture methods have been perfected such that the entire preimplantation period and the process of implantation can be followed in vitro. This protocol provides modifications for the analysis of clutches of embryos from heterozygous matings specifically for the purpose of distinguishing a preimplantation phenotype in homozygous mutants.
AB - Preimplantation embryo culture is a valuable approach to investigate a preimplantation lethal phenotype. Standard culture methods have been perfected such that the entire preimplantation period and the process of implantation can be followed in vitro. This protocol provides modifications for the analysis of clutches of embryos from heterozygous matings specifically for the purpose of distinguishing a preimplantation phenotype in homozygous mutants.
UR - http://www.scopus.com/inward/record.url?scp=85182276879&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85182276879&partnerID=8YFLogxK
U2 - 10.1101/pdb.prot108090
DO - 10.1101/pdb.prot108090
M3 - Article
C2 - 37932100
AN - SCOPUS:85182276879
SN - 1940-3402
VL - 2023
SP - 987
EP - 989
JO - Cold Spring Harbor protocols
JF - Cold Spring Harbor protocols
IS - 12
ER -