TY - JOUR
T1 - Placebo response in the treatment of Wwomen's sexual dysfunctions
T2 - A review and commentary
AU - Bradford, Andrea
AU - Meston, Cindy M.
N1 - Copyright:
Copyright 2010 Elsevier B.V., All rights reserved.
PY - 2009/5
Y1 - 2009/5
N2 - We reviewed the literature to determine the nature and magnitude of therapeutic response associated with placebo treatment in clinical trials for women's sexual dysfunction. We abstracted data from 16 articles to record the effect size associated with placebo treatment. In most of these studies, placebo recipients reported statistically significant improvements on one or more major endpoints relative to baseline. Although placebo responses varied across study populations and methodologies, within-group effect sizes were predominantly in the moderate range. Our findings suggest that post-menopausal women and women with hypoactive sexual desire disorder may be more likely to respond to placebo treatment.
AB - We reviewed the literature to determine the nature and magnitude of therapeutic response associated with placebo treatment in clinical trials for women's sexual dysfunction. We abstracted data from 16 articles to record the effect size associated with placebo treatment. In most of these studies, placebo recipients reported statistically significant improvements on one or more major endpoints relative to baseline. Although placebo responses varied across study populations and methodologies, within-group effect sizes were predominantly in the moderate range. Our findings suggest that post-menopausal women and women with hypoactive sexual desire disorder may be more likely to respond to placebo treatment.
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U2 - 10.1080/00926230802716302
DO - 10.1080/00926230802716302
M3 - Review article
C2 - 19360517
AN - SCOPUS:67650134494
SN - 0092-623X
VL - 35
SP - 164
EP - 181
JO - Journal of Sex and Marital Therapy
JF - Journal of Sex and Marital Therapy
IS - 3
ER -