Plasmapheresis in Patients With Heparin-induced Thrombocytopenia Requiring Ventricular Assist Device

Salvador R. Maffei; Harveen K. Lamba; Cassius Kwasi Mensah; Arthur Bracey; Andrew Civitello; Reynolds Delgado; Leo Simpson; Ajith Nair; O. H. Frazier; Jeffrey A. Morgan

doi:10.1016/j.athoracsur.2019.09.056

Plasmapheresis in Patients With Heparin-induced Thrombocytopenia Requiring Ventricular Assist Device

Salvador R. Maffei, Harveen K. Lamba, Cassius Kwasi Mensah, Arthur Bracey, Andrew Civitello, Reynolds Delgado, Leo Simpson, Ajith Nair, O. H. Frazier, Jeffrey A. Morgan

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Anticoagulation with unfractionated heparin is vital to reduce the risk of thromboembolic events during cardiopulmonary bypass and left ventricular assist device placement. However patients with heparin-induced thrombocytopenia are at risk of developing immune-mediated thrombotic events. We describe 2 patients with heparin-induced thrombocytopenia confirmed via serotonin release assay who were successfully treated with plasmapheresis exchange before left ventricular assist device placement.

Original language	English (US)
Pages (from-to)	e439-e440
Journal	Annals of Thoracic Surgery
Volume	109
Issue number	6
DOIs	https://doi.org/10.1016/j.athoracsur.2019.09.056
State	Published - Jun 2020
Externally published	Yes

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine

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10.1016/j.athoracsur.2019.09.056

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title = "Plasmapheresis in Patients With Heparin-induced Thrombocytopenia Requiring Ventricular Assist Device",

abstract = "Anticoagulation with unfractionated heparin is vital to reduce the risk of thromboembolic events during cardiopulmonary bypass and left ventricular assist device placement. However patients with heparin-induced thrombocytopenia are at risk of developing immune-mediated thrombotic events. We describe 2 patients with heparin-induced thrombocytopenia confirmed via serotonin release assay who were successfully treated with plasmapheresis exchange before left ventricular assist device placement.",

author = "Maffei, {Salvador R.} and Lamba, {Harveen K.} and Mensah, {Cassius Kwasi} and Arthur Bracey and Andrew Civitello and Reynolds Delgado and Leo Simpson and Ajith Nair and Frazier, {O. H.} and Morgan, {Jeffrey A.}",

note = "Publisher Copyright: {\textcopyright} 2020 The Society of Thoracic Surgeons",

year = "2020",

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doi = "10.1016/j.athoracsur.2019.09.056",

language = "English (US)",

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T1 - Plasmapheresis in Patients With Heparin-induced Thrombocytopenia Requiring Ventricular Assist Device

AU - Maffei, Salvador R.

AU - Lamba, Harveen K.

AU - Mensah, Cassius Kwasi

AU - Bracey, Arthur

AU - Civitello, Andrew

AU - Delgado, Reynolds

AU - Simpson, Leo

AU - Nair, Ajith

AU - Frazier, O. H.

AU - Morgan, Jeffrey A.

PY - 2020/6

Y1 - 2020/6

N2 - Anticoagulation with unfractionated heparin is vital to reduce the risk of thromboembolic events during cardiopulmonary bypass and left ventricular assist device placement. However patients with heparin-induced thrombocytopenia are at risk of developing immune-mediated thrombotic events. We describe 2 patients with heparin-induced thrombocytopenia confirmed via serotonin release assay who were successfully treated with plasmapheresis exchange before left ventricular assist device placement.

AB - Anticoagulation with unfractionated heparin is vital to reduce the risk of thromboembolic events during cardiopulmonary bypass and left ventricular assist device placement. However patients with heparin-induced thrombocytopenia are at risk of developing immune-mediated thrombotic events. We describe 2 patients with heparin-induced thrombocytopenia confirmed via serotonin release assay who were successfully treated with plasmapheresis exchange before left ventricular assist device placement.

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SP - e439-e440

JO - Annals of Thoracic Surgery

JF - Annals of Thoracic Surgery

IS - 6

ER -

Plasmapheresis in Patients With Heparin-induced Thrombocytopenia Requiring Ventricular Assist Device

Abstract

ASJC Scopus subject areas

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