TY - JOUR
T1 - Portal vein embolization in preparation for major hepatic resection
T2 - Evolution of a new standard of care
AU - Madoff, David C.
AU - Abdalla, Eddie K.
AU - Vauthey, Jean Nicolas
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2005/6
Y1 - 2005/6
N2 - Portal vein (PV) embolization (PVE) is gaining acceptance in the preoperative management of patients selected for major hepatic resection. PVE redirects portal blood flow to the intended liver remnant to induce hypertrophy of the nondiseased portion of the liver and thereby reduce complications and shorten hospital stays after resection. This article reviews the rationale and existing literature on PVE, including the mechanisms of liver regeneration, the pathophysiology of PVE, the imaging techniques used to measure liver volumes and estimate functional hepatic reserve, and the technical aspects of PVE, including approaches and embolic agents used. In addition, the indications and contraindications for performing PVE in patients with and without chronic liver disease and the multidiscipliriary approach required for the treatment of these complex cases are emphasized.
AB - Portal vein (PV) embolization (PVE) is gaining acceptance in the preoperative management of patients selected for major hepatic resection. PVE redirects portal blood flow to the intended liver remnant to induce hypertrophy of the nondiseased portion of the liver and thereby reduce complications and shorten hospital stays after resection. This article reviews the rationale and existing literature on PVE, including the mechanisms of liver regeneration, the pathophysiology of PVE, the imaging techniques used to measure liver volumes and estimate functional hepatic reserve, and the technical aspects of PVE, including approaches and embolic agents used. In addition, the indications and contraindications for performing PVE in patients with and without chronic liver disease and the multidiscipliriary approach required for the treatment of these complex cases are emphasized.
UR - http://www.scopus.com/inward/record.url?scp=20544468528&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=20544468528&partnerID=8YFLogxK
U2 - 10.1097/01.RVI.0000159543.28222.73
DO - 10.1097/01.RVI.0000159543.28222.73
M3 - Review article
C2 - 15947041
AN - SCOPUS:20544468528
SN - 1051-0443
VL - 16
SP - 779
EP - 790
JO - Journal of Vascular and Interventional Radiology
JF - Journal of Vascular and Interventional Radiology
IS - 6
ER -