Presynaptic mGluR5 receptor controls glutamatergic input through protein kinase C-NMDA receptors in paclitaxelinduced neuropathic pain

Medicine & Life Sciences

• Receptors for Activated C Kinase 100%
• Presynaptic Receptors 89%
• Excitatory Postsynaptic Potentials 75%
• Neuralgia 67%
• N-Methyl-D-Aspartate Receptors 65%
• Paclitaxel 54%
• 3,5-dihydroxyphenylglycine 52%
• Painful Neuropathy 32%
• Posterior Horn Cells 29%
• pyridine 28%
• Protein Kinase C 20%
• 6-methyl-2-(phenylethynyl)pyridine 18%
• Spinal Cord 17%
• Metabotropic Glutamate 5 Receptor 16%
• metabotropic glutamate receptor type 1 15%
• Metabotropic Glutamate Receptors 13%
• Neurotransmitter Receptor 13%
• Synaptosomes 13%
• Spinal Nerve Roots 12%
• Drug Therapy 12%
• Cancer Survivors 11%
• Spinal Ganglia 11%
• Peripheral Nervous System Diseases 11%
• Neuronal Plasticity 10%
• Chronic Pain 9%
• Hypersensitivity 8%
• Pain 6%
• Pharmaceutical Preparations 4%
• Therapeutics 1%

Chemistry

• (S)-3,5-dihydroxyphenylglycine 43%
• 2-methyl-6-(phenylethynyl)pyridine 43%
• Antagonist 40%
• Intrathecal 37%
• Protein 26%
• Plastic Property 25%
• Agonist 20%
• Antineoplastic Agent 19%