Primary diffuse large B-cell non-Hodgkin lymphoma of the paranasal sinuses: A report of 14 cases

C. Oprea; C. Cainap; R. Azoulay; E. Assaf; E. Jabbour; S. Koscielny; S. Lapusan; D. Vanel; J. Bosq; V. Ribrag

doi:10.1111/j.1365-2141.2005.05787.x

Primary diffuse large B-cell non-Hodgkin lymphoma of the paranasal sinuses: A report of 14 cases

C. Oprea, C. Cainap, R. Azoulay, E. Assaf, E. Jabbour, S. Koscielny, S. Lapusan, D. Vanel, J. Bosq, V. Ribrag

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Sinonasal lymphoma (SL) is a rare form of extranodal lymphoma. Of 33 SL cases, 14 consecutive diffuse large B-cell lymphomas were treated with CHOP (adriamycin, cyclophosphamide, vincristine and prednisone) or CHOP-like chemotherapy regimen. Ten achieved complete remission (CR) and three achieved a partial remission. With a median follow-up period of 80 months, seven patients relapsed or progressed [one case including central nervous system (CNS) progression]. Four of the relapses involved the CNS. Eight patients were alive, including seven in CR and six patients had died of their lymphoma. This observation strongly suggests that CNS prophylaxis should be used in SL.

Original language	English (US)
Pages (from-to)	468-471
Number of pages	4
Journal	British Journal of Haematology
Volume	131
Issue number	4
DOIs	https://doi.org/10.1111/j.1365-2141.2005.05787.x
State	Published - Nov 2005
Externally published	Yes

Keywords

Chemotherapy
Primary paranasal sinuses lymphoma
Prognostic factors
Relapse

ASJC Scopus subject areas

Hematology

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10.1111/j.1365-2141.2005.05787.x

Cite this

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title = "Primary diffuse large B-cell non-Hodgkin lymphoma of the paranasal sinuses: A report of 14 cases",

abstract = "Sinonasal lymphoma (SL) is a rare form of extranodal lymphoma. Of 33 SL cases, 14 consecutive diffuse large B-cell lymphomas were treated with CHOP (adriamycin, cyclophosphamide, vincristine and prednisone) or CHOP-like chemotherapy regimen. Ten achieved complete remission (CR) and three achieved a partial remission. With a median follow-up period of 80 months, seven patients relapsed or progressed [one case including central nervous system (CNS) progression]. Four of the relapses involved the CNS. Eight patients were alive, including seven in CR and six patients had died of their lymphoma. This observation strongly suggests that CNS prophylaxis should be used in SL.",

keywords = "Chemotherapy, Primary paranasal sinuses lymphoma, Prognostic factors, Relapse",

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AU - Oprea, C.

AU - Cainap, C.

AU - Azoulay, R.

AU - Assaf, E.

AU - Jabbour, E.

AU - Koscielny, S.

AU - Lapusan, S.

AU - Vanel, D.

AU - Bosq, J.

AU - Ribrag, V.

PY - 2005/11

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N2 - Sinonasal lymphoma (SL) is a rare form of extranodal lymphoma. Of 33 SL cases, 14 consecutive diffuse large B-cell lymphomas were treated with CHOP (adriamycin, cyclophosphamide, vincristine and prednisone) or CHOP-like chemotherapy regimen. Ten achieved complete remission (CR) and three achieved a partial remission. With a median follow-up period of 80 months, seven patients relapsed or progressed [one case including central nervous system (CNS) progression]. Four of the relapses involved the CNS. Eight patients were alive, including seven in CR and six patients had died of their lymphoma. This observation strongly suggests that CNS prophylaxis should be used in SL.

AB - Sinonasal lymphoma (SL) is a rare form of extranodal lymphoma. Of 33 SL cases, 14 consecutive diffuse large B-cell lymphomas were treated with CHOP (adriamycin, cyclophosphamide, vincristine and prednisone) or CHOP-like chemotherapy regimen. Ten achieved complete remission (CR) and three achieved a partial remission. With a median follow-up period of 80 months, seven patients relapsed or progressed [one case including central nervous system (CNS) progression]. Four of the relapses involved the CNS. Eight patients were alive, including seven in CR and six patients had died of their lymphoma. This observation strongly suggests that CNS prophylaxis should be used in SL.

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KW - Primary paranasal sinuses lymphoma

KW - Prognostic factors

KW - Relapse

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Primary diffuse large B-cell non-Hodgkin lymphoma of the paranasal sinuses: A report of 14 cases

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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