Abstract
Primary follicular lymphoma of the testis in childhood is extremely rare. To our knowledge, only 5 cases have been reported to date. We report a case in a 6-year-old boy who presented with painless right scrotal enlargement. Right radical orchiectomy revealed a follicular large cell lymphoma with diffuse areas confined to the testis and epididymis, clinical stage IE. Immunohistochemical stains demonstrated that the neoplastic cells were of B-cell lineage, positive for CD10, CD20, CD79a, and BCL-6. Staining for CD21 accentuated networks of dendritic reticulum cells within the nodules. The cells were negative for BCL-2, p53, and T-cell antigens. There was no evidence of the t(14;18) detected by polymerase chain reaction. The data suggest that follicular lymphoma of the testis in children has a different pathogenesis than follicular lymphoma in adults.
Original language | English (US) |
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Pages (from-to) | 551-554 |
Number of pages | 4 |
Journal | Archives of Pathology and Laboratory Medicine |
Volume | 125 |
Issue number | 4 |
State | Published - 2001 |
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Medical Laboratory Technology