Primary Osteosarcoma of the Breast: Pathophysiology and Imaging Review

Bilal Mujtaba; Sameh M. Nassar; Rizwan Aslam; Naveen Garg; John E. Madewell; Ahmed Taher; Abdelrahman k. Hanafy; Gary Whitman

doi:10.1067/j.cpradiol.2019.01.001

Primary Osteosarcoma of the Breast: Pathophysiology and Imaging Review

Bilal Mujtaba, Sameh M. Nassar, Rizwan Aslam, Naveen Garg, John E. Madewell, Ahmed Taher, Abdelrahman k. Hanafy, Gary Whitman

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Abstract

Extraskeletal osteosarcoma are rare malignant mesenchymal neoplasms of soft tissues representing around 1% of all soft tissue. The exact mechanism of tumorigenesis of primary breast osteosarcoma is still unclear. However, most of the cases develop without a recognized etiologic factor. Primary osteosarcoma of the breast is often initially misdiagnosed as breast fibroadenoma. Different imaging modalities and pathology play important role in differentiating breast osteosarcoma from other benign and malignant lesions of the breast resulting in dramatic change in the management.

Original language	English (US)
Pages (from-to)	116-123
Number of pages	8
Journal	Current Problems in Diagnostic Radiology
Volume	49
Issue number	2
DOIs	https://doi.org/10.1067/j.cpradiol.2019.01.001
State	Published - Mar 1 2020

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1067/j.cpradiol.2019.01.001

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title = "Primary Osteosarcoma of the Breast: Pathophysiology and Imaging Review",

abstract = "Extraskeletal osteosarcoma are rare malignant mesenchymal neoplasms of soft tissues representing around 1% of all soft tissue. The exact mechanism of tumorigenesis of primary breast osteosarcoma is still unclear. However, most of the cases develop without a recognized etiologic factor. Primary osteosarcoma of the breast is often initially misdiagnosed as breast fibroadenoma. Different imaging modalities and pathology play important role in differentiating breast osteosarcoma from other benign and malignant lesions of the breast resulting in dramatic change in the management.",

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AU - Aslam, Rizwan

AU - Garg, Naveen

AU - Madewell, John E.

AU - Taher, Ahmed

AU - Hanafy, Abdelrahman k.

AU - Whitman, Gary

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N2 - Extraskeletal osteosarcoma are rare malignant mesenchymal neoplasms of soft tissues representing around 1% of all soft tissue. The exact mechanism of tumorigenesis of primary breast osteosarcoma is still unclear. However, most of the cases develop without a recognized etiologic factor. Primary osteosarcoma of the breast is often initially misdiagnosed as breast fibroadenoma. Different imaging modalities and pathology play important role in differentiating breast osteosarcoma from other benign and malignant lesions of the breast resulting in dramatic change in the management.

AB - Extraskeletal osteosarcoma are rare malignant mesenchymal neoplasms of soft tissues representing around 1% of all soft tissue. The exact mechanism of tumorigenesis of primary breast osteosarcoma is still unclear. However, most of the cases develop without a recognized etiologic factor. Primary osteosarcoma of the breast is often initially misdiagnosed as breast fibroadenoma. Different imaging modalities and pathology play important role in differentiating breast osteosarcoma from other benign and malignant lesions of the breast resulting in dramatic change in the management.

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Primary Osteosarcoma of the Breast: Pathophysiology and Imaging Review

Abstract

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