TY - JOUR
T1 - Primary Salivary Gland Type Tumors of the Thymus
AU - Kalhor, Neda
AU - Weissferdt, Annikka
AU - Moran, Cesar A.
N1 - Publisher Copyright:
Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - The existence of primary salivary gland type tumors (SGTs), similar to those occurring in the major salivary glands, is well known in the thoracic cavity. When they occur in this anatomic area, these tumors more commonly arise from the lung. However, the existence of these tumors primarily affecting the thymus, although recognized in the literature, is rather not well documented or known. In addition, contrary to the primary lung SGTs, which are predominantly of the malignant type, these tumors when occur in thymus encompass a wider spectrum of biology ranging from benign to low grade, and high grade malignancy. The recognition of SGTs in the thymus, even though rare, is important to properly address treatment and prognosis. Herein, we will discuss the numerous benign a malignant SGTs that have been described in the thymus and highlight the difficulty that these tumors may pose when occurring in the thymic area.
AB - The existence of primary salivary gland type tumors (SGTs), similar to those occurring in the major salivary glands, is well known in the thoracic cavity. When they occur in this anatomic area, these tumors more commonly arise from the lung. However, the existence of these tumors primarily affecting the thymus, although recognized in the literature, is rather not well documented or known. In addition, contrary to the primary lung SGTs, which are predominantly of the malignant type, these tumors when occur in thymus encompass a wider spectrum of biology ranging from benign to low grade, and high grade malignancy. The recognition of SGTs in the thymus, even though rare, is important to properly address treatment and prognosis. Herein, we will discuss the numerous benign a malignant SGTs that have been described in the thymus and highlight the difficulty that these tumors may pose when occurring in the thymic area.
KW - mediastinum
KW - salivary gland
KW - thoracic
KW - thymic
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U2 - 10.1097/PAP.0000000000000132
DO - 10.1097/PAP.0000000000000132
M3 - Review article
C2 - 27941539
AN - SCOPUS:85007383421
SN - 1072-4109
VL - 24
SP - 15
EP - 23
JO - Advances in anatomic pathology
JF - Advances in anatomic pathology
IS - 1
ER -