TY - JOUR
T1 - Principles and Applications of Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy
AU - Abel, Stephen
AU - Lee, Soyoung
AU - Ludmir, Ethan B.
AU - Verma, Vivek
N1 - Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/12
Y1 - 2019/12
N2 - Stereotactic radiation therapy (RT) involves the delivery of high dose-per-fraction treatments to small intracranial (stereotactic radiosurgery [SRS]) and extracranial (stereotactic body radiotherapy [SBRT]) sites. SRS and SBRT share several overarching principles that differentiate stereotactic RT from conventionally fractionated radiation techniques. This review describes historical aspects of SRS/SBRT and definitions thereof, and a comparison with more modern semantics. Key principles of the stereotactic radiotherapeutic modalities are discussed, followed by an overview of the technical considerations involved. Lastly, the accepted appropriate clinical indications for stereotactic RT are outlined, and the potential role of stereotactic treatment in future oncologic management are also discussed.
AB - Stereotactic radiation therapy (RT) involves the delivery of high dose-per-fraction treatments to small intracranial (stereotactic radiosurgery [SRS]) and extracranial (stereotactic body radiotherapy [SBRT]) sites. SRS and SBRT share several overarching principles that differentiate stereotactic RT from conventionally fractionated radiation techniques. This review describes historical aspects of SRS/SBRT and definitions thereof, and a comparison with more modern semantics. Key principles of the stereotactic radiotherapeutic modalities are discussed, followed by an overview of the technical considerations involved. Lastly, the accepted appropriate clinical indications for stereotactic RT are outlined, and the potential role of stereotactic treatment in future oncologic management are also discussed.
KW - Stereotactic ablative radiotherapy
KW - Stereotactic body radiation therapy
KW - Stereotactic radiosurgery
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U2 - 10.1016/j.hoc.2019.08.007
DO - 10.1016/j.hoc.2019.08.007
M3 - Review article
C2 - 31668215
AN - SCOPUS:85072705722
SN - 0889-8588
VL - 33
SP - 977
EP - 987
JO - Hematology/Oncology Clinics of North America
JF - Hematology/Oncology Clinics of North America
IS - 6
ER -