Prognosis and Biology in Esthesioneuroblastoma: the Emerging Role of Hyams Grading System

Rami E. Saade, Ehab Y. Hanna, Diana Bell

Research output: Contribution to journalReview articlepeer-review

50 Scopus citations

Abstract

Esthesioneuroblastoma is a sinonasal tumor with distinct clinicopathologic features, multiple facets, and a spectrum of behavior. Characterization of this disease is challenging, and clinically, several staging systems have been used with no consensus on a single scheme. Recently, the Hyams histological grading system has emerged as a promising prognostication tool that offers an added value to stage. This review addresses prognosis and biology in esthesioneuroblastoma. More specifically, we sought to present a critical appraisal on the value of each of these stratification systems, stage vs. grade, in identifying risk groups and guiding management.

Original languageEnglish (US)
Pages (from-to)1-5
Number of pages5
JournalCurrent oncology reports
Volume17
Issue number1
DOIs
StatePublished - Jan 2015

Keywords

  • Esthesioneuroblastoma
  • Grade
  • Hyams
  • Kadish
  • Morita
  • Olfactory Neuroblastoma
  • Outcome
  • Prognosis
  • Stage

ASJC Scopus subject areas

  • Oncology

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