Prolactin-releasing peptide

Steven H. Lin

doi:10.1007/400_2007_048

Prolactin-releasing peptide

Steven H. Lin

Research output: Chapter in Book/Report/Conference proceeding › Chapter

22 Scopus citations

Abstract

Prolactin-releasing peptide (PrRP) was initially isolated from the bovine hypothalamus as an activating component that stimulated arachidonic acid release from cells stably expressing the orphan G protein-coupled receptor hGR3 (Hinuma et al. 1998) [also known as GPR10 (Marchese et al. 1995), or UHR-1 for the rat orthologue (Welch et al. 1995)]. Initially touted as a prolactin-releasing factor (therefore aptly named prolactin-releasing peptide), the perspective on the function of this peptide in the organism has been greatly expanded. Over 120 papers have been published on this subject since its initial discovery in 1998. Herein I review the state of knowledge of the PrRP system, its putative function in the organism, and implications for therapy.

Original language	English (US)
Title of host publication	Orphan G Protein-Coupled Receptors and Novel Neuropeptides
Editors	Olivier Civelli, Qun-Yong Zhou
Pages	57-88
Number of pages	32
DOIs	https://doi.org/10.1007/400_2007_048
State	Published - 2008
Externally published	Yes

Publication series

Name	Results and Problems in Cell Differentiation
Volume	46
ISSN (Print)	0080-1844
ISSN (Electronic)	1861-0412

ASJC Scopus subject areas

Developmental Biology
Cell Biology

Access to Document

10.1007/400_2007_048

Cite this

@inbook{4f46045984b842c994bd6b544f2ee95d,

title = "Prolactin-releasing peptide",

abstract = "Prolactin-releasing peptide (PrRP) was initially isolated from the bovine hypothalamus as an activating component that stimulated arachidonic acid release from cells stably expressing the orphan G protein-coupled receptor hGR3 (Hinuma et al. 1998) [also known as GPR10 (Marchese et al. 1995), or UHR-1 for the rat orthologue (Welch et al. 1995)]. Initially touted as a prolactin-releasing factor (therefore aptly named prolactin-releasing peptide), the perspective on the function of this peptide in the organism has been greatly expanded. Over 120 papers have been published on this subject since its initial discovery in 1998. Herein I review the state of knowledge of the PrRP system, its putative function in the organism, and implications for therapy.",

author = "Lin, {Steven H.}",

year = "2008",

doi = "10.1007/400_2007_048",

language = "English (US)",

isbn = "9783540783503",

series = "Results and Problems in Cell Differentiation",

pages = "57--88",

editor = "Olivier Civelli and Qun-Yong Zhou",

booktitle = "Orphan G Protein-Coupled Receptors and Novel Neuropeptides",

}

TY - CHAP

T1 - Prolactin-releasing peptide

AU - Lin, Steven H.

PY - 2008

Y1 - 2008

N2 - Prolactin-releasing peptide (PrRP) was initially isolated from the bovine hypothalamus as an activating component that stimulated arachidonic acid release from cells stably expressing the orphan G protein-coupled receptor hGR3 (Hinuma et al. 1998) [also known as GPR10 (Marchese et al. 1995), or UHR-1 for the rat orthologue (Welch et al. 1995)]. Initially touted as a prolactin-releasing factor (therefore aptly named prolactin-releasing peptide), the perspective on the function of this peptide in the organism has been greatly expanded. Over 120 papers have been published on this subject since its initial discovery in 1998. Herein I review the state of knowledge of the PrRP system, its putative function in the organism, and implications for therapy.

AB - Prolactin-releasing peptide (PrRP) was initially isolated from the bovine hypothalamus as an activating component that stimulated arachidonic acid release from cells stably expressing the orphan G protein-coupled receptor hGR3 (Hinuma et al. 1998) [also known as GPR10 (Marchese et al. 1995), or UHR-1 for the rat orthologue (Welch et al. 1995)]. Initially touted as a prolactin-releasing factor (therefore aptly named prolactin-releasing peptide), the perspective on the function of this peptide in the organism has been greatly expanded. Over 120 papers have been published on this subject since its initial discovery in 1998. Herein I review the state of knowledge of the PrRP system, its putative function in the organism, and implications for therapy.

UR - http://www.scopus.com/inward/record.url?scp=43849084352&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=43849084352&partnerID=8YFLogxK

U2 - 10.1007/400_2007_048

DO - 10.1007/400_2007_048

M3 - Chapter

C2 - 18204826

AN - SCOPUS:43849084352

SN - 9783540783503

T3 - Results and Problems in Cell Differentiation

SP - 57

EP - 88

BT - Orphan G Protein-Coupled Receptors and Novel Neuropeptides

A2 - Civelli, Olivier

A2 - Zhou, Qun-Yong

ER -

Prolactin-releasing peptide

Abstract

Publication series

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this