TY - JOUR
T1 - Pulmonary artery angiosarcoma
T2 - A clinicopathologic and radiological correlation
AU - Huo, Lei
AU - Lai, Syeling
AU - Gladish, Gregory
AU - Czerniak, Bogdan A.
AU - Moran, Cesar A.
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2005/8
Y1 - 2005/8
N2 - A 69-year-old man presented with cough, shortness of breath, and fatigue. He was initially treated for allergies and then for pulmonary embolism. Radiologically, a tumor mass was found to occlude the right pulmonary artery and involve the pulmonary trunk. A right pneumonectomy was performed. Histologically, a cellular malignant spindle and epithelioid tumor with areas of necrosis and brisk mitotic activity was seen. In some areas, the tumor appeared to form vascular channels. Focal osteosarcomatous differentiation was present. Immunohistochemical studies were performed including vimentin, smooth muscle actin, desmin, CD31, CD34, S100, and pan-cytokeratin. The tumor cells were positive for CD31 and vimentin and negative for pan-cytokeratin, CD34, and S100. Two months after surgery, the patient was alive and well.
AB - A 69-year-old man presented with cough, shortness of breath, and fatigue. He was initially treated for allergies and then for pulmonary embolism. Radiologically, a tumor mass was found to occlude the right pulmonary artery and involve the pulmonary trunk. A right pneumonectomy was performed. Histologically, a cellular malignant spindle and epithelioid tumor with areas of necrosis and brisk mitotic activity was seen. In some areas, the tumor appeared to form vascular channels. Focal osteosarcomatous differentiation was present. Immunohistochemical studies were performed including vimentin, smooth muscle actin, desmin, CD31, CD34, S100, and pan-cytokeratin. The tumor cells were positive for CD31 and vimentin and negative for pan-cytokeratin, CD34, and S100. Two months after surgery, the patient was alive and well.
KW - Angiosarcoma
KW - Intimal sarcoma
KW - Pulmonary artery
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U2 - 10.1016/j.anndiagpath.2005.04.012
DO - 10.1016/j.anndiagpath.2005.04.012
M3 - Article
C2 - 16084454
AN - SCOPUS:23444453731
SN - 1092-9134
VL - 9
SP - 209
EP - 214
JO - Annals of Diagnostic Pathology
JF - Annals of Diagnostic Pathology
IS - 4
ER -