Abstract
Approximately half of all cancer patients receive radiation therapy as part of their oncologic treatment. Radiation-associated sarcomas occur in fewer than 1% of patients who receive radiation therapy but account for up to 5% of all sarcomas. As the use of radiation has increased in the past few decades and overall oncologic outcomes are improving, the incidence of radiation-associated sarcomas is also expected to increase. Historically, radiation-associated sarcomas have been associated with poor outcomes but recent data suggest the prognosis is improving. Distinguishing the sarcoma from the primary malignancy is a major diagnostic criterion.
Original language | English (US) |
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Pages (from-to) | 139-148 |
Number of pages | 10 |
Journal | Surgical Pathology Clinics |
Volume | 12 |
Issue number | 1 |
DOIs | |
State | Published - Mar 2019 |
Externally published | Yes |
Keywords
- Immunohistochemistry
- Molecular genetics
- Radiation
- Radiation-associated
- Sarcoma
- Secondary malignancy
- Soft tissue
- Tumor
ASJC Scopus subject areas
- Surgery
- Pathology and Forensic Medicine