TY - JOUR
T1 - Radiation injury
T2 - imaging findings in the chest, abdomen and pelvis after therapeutic radiation.
AU - Iyer, R.
AU - Jhingran, A.
PY - 2006
Y1 - 2006
N2 - Radiation may be used as adjuvant or primary therapy in a variety of tumors in the chest, abdomen and pelvis. Therapeutic radiation affects not only malignant tumors but also surrounding normal tissues. The risk of injury depends on the size, number and frequency of radiation fractions, volume of irradiated tissue, duration of treatment, and method of radiation delivery. Concomitant chemotherapy can act synergistically to produce injury. Other predisposing factors include infection, prior surgery and chronic illness like hypertension, diabetes mellitus and atherosclerosis. Radiation changes vary, based on the target organ and the time from completion of therapy. While most serious complications related to radiotherapy are relatively uncommon, given the number of patients that are treated and the relatively long latency period for development of radiation changes, follow-up imaging studies frequently have findings that should be recognized as radiation related. Familiarity with the spectrum of imaging findings after radiation injury permits differentiation from other etiologies such as recurrent malignancy. The following will discuss imaging findings that may be seen during imaging surveillance in patients with malignancy affecting the chest, abdomen and pelvis. (c) International Cancer Imaging Society.
AB - Radiation may be used as adjuvant or primary therapy in a variety of tumors in the chest, abdomen and pelvis. Therapeutic radiation affects not only malignant tumors but also surrounding normal tissues. The risk of injury depends on the size, number and frequency of radiation fractions, volume of irradiated tissue, duration of treatment, and method of radiation delivery. Concomitant chemotherapy can act synergistically to produce injury. Other predisposing factors include infection, prior surgery and chronic illness like hypertension, diabetes mellitus and atherosclerosis. Radiation changes vary, based on the target organ and the time from completion of therapy. While most serious complications related to radiotherapy are relatively uncommon, given the number of patients that are treated and the relatively long latency period for development of radiation changes, follow-up imaging studies frequently have findings that should be recognized as radiation related. Familiarity with the spectrum of imaging findings after radiation injury permits differentiation from other etiologies such as recurrent malignancy. The following will discuss imaging findings that may be seen during imaging surveillance in patients with malignancy affecting the chest, abdomen and pelvis. (c) International Cancer Imaging Society.
UR - http://www.scopus.com/inward/record.url?scp=39049187441&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=39049187441&partnerID=8YFLogxK
U2 - 10.1102/1470-7330.2006.9095
DO - 10.1102/1470-7330.2006.9095
M3 - Article
C2 - 17114067
AN - SCOPUS:39049187441
SN - 1740-5025
VL - 6
SP - S131-139
JO - Cancer imaging : the official publication of the International Cancer Imaging Society
JF - Cancer imaging : the official publication of the International Cancer Imaging Society
ER -