Radiation Therapy for Leptomeningeal Disease

Samantha M. Buszek; Caroline Chung

doi:10.1007/978-3-031-14291-8_6

Radiation Therapy for Leptomeningeal Disease

Samantha M. Buszek, Caroline Chung

Radiation Oncology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Leptomeningeal disease (LMD) occurs in approximately 5% of all cancer patients, presenting most commonly in primary diagnoses of breast cancer, lung cancer, gastrointestinal tract malignancies, and melanoma. Radiation therapy (RT) is commonly incorporated as a part of the multimodal approach in the treatment of LMD and has traditionally been recommended for patients with bulky or symptomatic metastatic sites of LMD to provide symptom relief, CSF flow correction, or for debulking of disease to facilitate further systemic therapy. Several RT techniques have been utilized for the treatment of LMD, including involved-field RT, whole brain RT, and craniospinal irradiation.

Original language	English (US)
Title of host publication	Radiopharmaceuticals in the Management of Leptomeningeal Metastasis
Publisher	Springer International Publishing
Pages	125-141
Number of pages	17
ISBN (Electronic)	9783031142918
ISBN (Print)	9783031142901
DOIs	https://doi.org/10.1007/978-3-031-14291-8_6
State	Published - Jan 1 2022

Keywords

Cerebrospinal fluid block
Craniospinal irradiation
Involved-field radiotherapy
Radiotherapy
Whole brain radiotherapy

ASJC Scopus subject areas

General Medicine

Access to Document

10.1007/978-3-031-14291-8_6

Cite this

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title = "Radiation Therapy for Leptomeningeal Disease",

abstract = "Leptomeningeal disease (LMD) occurs in approximately 5% of all cancer patients, presenting most commonly in primary diagnoses of breast cancer, lung cancer, gastrointestinal tract malignancies, and melanoma. Radiation therapy (RT) is commonly incorporated as a part of the multimodal approach in the treatment of LMD and has traditionally been recommended for patients with bulky or symptomatic metastatic sites of LMD to provide symptom relief, CSF flow correction, or for debulking of disease to facilitate further systemic therapy. Several RT techniques have been utilized for the treatment of LMD, including involved-field RT, whole brain RT, and craniospinal irradiation.",

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AU - Chung, Caroline

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N2 - Leptomeningeal disease (LMD) occurs in approximately 5% of all cancer patients, presenting most commonly in primary diagnoses of breast cancer, lung cancer, gastrointestinal tract malignancies, and melanoma. Radiation therapy (RT) is commonly incorporated as a part of the multimodal approach in the treatment of LMD and has traditionally been recommended for patients with bulky or symptomatic metastatic sites of LMD to provide symptom relief, CSF flow correction, or for debulking of disease to facilitate further systemic therapy. Several RT techniques have been utilized for the treatment of LMD, including involved-field RT, whole brain RT, and craniospinal irradiation.

AB - Leptomeningeal disease (LMD) occurs in approximately 5% of all cancer patients, presenting most commonly in primary diagnoses of breast cancer, lung cancer, gastrointestinal tract malignancies, and melanoma. Radiation therapy (RT) is commonly incorporated as a part of the multimodal approach in the treatment of LMD and has traditionally been recommended for patients with bulky or symptomatic metastatic sites of LMD to provide symptom relief, CSF flow correction, or for debulking of disease to facilitate further systemic therapy. Several RT techniques have been utilized for the treatment of LMD, including involved-field RT, whole brain RT, and craniospinal irradiation.

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KW - Involved-field radiotherapy

KW - Radiotherapy

KW - Whole brain radiotherapy

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Radiation Therapy for Leptomeningeal Disease

Abstract

Keywords

ASJC Scopus subject areas

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