Abstract
The rationales for published intrathecal radionuclide for leptomeningeal metastasis (LM) therapy trials with radiopharmaceuticals are reviewed. The radioactivity dosing schemes, efficacy, and toxicity profiles are compared. The potential use of radiation dosimetry to guide intrathecal radionuclide therapy is also reviewed. The trends, practical, and logistic aspects of intrathecal radionuclide therapy of LM are outlined.
Original language | English (US) |
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Title of host publication | Radiopharmaceuticals in the Management of Leptomeningeal Metastasis |
Publisher | Springer International Publishing |
Pages | 149-159 |
Number of pages | 11 |
ISBN (Electronic) | 9783031142918 |
ISBN (Print) | 9783031142901 |
DOIs | |
State | Published - Jan 1 2022 |
Keywords
- Au-198
- Colloid
- I-125-IUDR
- I-131 Monoclonal antibody
- Omburtamab
- P-32
ASJC Scopus subject areas
- General Medicine