Radionuclide Leptomeningeal Metastasis Therapy Trials

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The rationales for published intrathecal radionuclide for leptomeningeal metastasis (LM) therapy trials with radiopharmaceuticals are reviewed. The radioactivity dosing schemes, efficacy, and toxicity profiles are compared. The potential use of radiation dosimetry to guide intrathecal radionuclide therapy is also reviewed. The trends, practical, and logistic aspects of intrathecal radionuclide therapy of LM are outlined.

Original languageEnglish (US)
Title of host publicationRadiopharmaceuticals in the Management of Leptomeningeal Metastasis
PublisherSpringer International Publishing
Pages149-159
Number of pages11
ISBN (Electronic)9783031142918
ISBN (Print)9783031142901
DOIs
StatePublished - Jan 1 2022

Keywords

  • Au-198
  • Colloid
  • I-125-IUDR
  • I-131 Monoclonal antibody
  • Omburtamab
  • P-32

ASJC Scopus subject areas

  • General Medicine

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