Abstract
This chapter offers an in-depth exploration of advancements in imaging biomarker research within the realm of radiotherapy. It emphasizes radiomic models with high-dimensional feature sets tailored for supervised machine learning prediction. Specifically, this chapter reports on quantitative image biomarkers extracted from computed tomography, positron emission tomography, and magnetic resonance imaging modalities to formulate predictive models for clinical outcomes. Part 1 covers pre-treatment image biomarkers and their utility in predicting tumor response and normal tissue toxicity. Part 2 examines the change of image biomarkers during treatment, assessing their connection to dose and eventual outcomes. Part 3 addresses standardization, validation, interpretation, and practical applications of these biomarkers and models.
Original language | English (US) |
---|---|
Title of host publication | Machine Learning and Artificial Intelligence in Radiation Oncology |
Subtitle of host publication | A Guide for Clinicians |
Publisher | Elsevier |
Pages | 239-315 |
Number of pages | 77 |
ISBN (Electronic) | 9780128220009 |
DOIs | |
State | Published - Jan 1 2023 |
Keywords
- Medical imaging
- Medical physics
- Medical research
- Neoplasia
- Omics
ASJC Scopus subject areas
- General Agricultural and Biological Sciences
- General Biochemistry, Genetics and Molecular Biology