Abstract
WE PRESENT THREE cases of histologically benign meningiomas with a rapid and known time course to the development of symptoms. Tumor doubling time calculated from sequential computed tomographic scans and computer-assisted image analysis of proliferating cell nuclear antigen reactivity suggested rapid growth. Feulgen staining indicated deoxyribonucleic acid aneuploidy. Tests for progesterone and estrogen receptor immunoreactivity were negative. These cases are noteworthy for their uncharacteristically rapid growth in the absence of histological evidence of atypia.
Original language | English (US) |
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Pages (from-to) | 998-1001 |
Number of pages | 4 |
Journal | Neurosurgery |
Volume | 37 |
Issue number | 5 |
DOIs | |
State | Published - 1995 |
Externally published | Yes |
Keywords
- Cell kinetics
- Deoxyribonucleic acid ploidy
- Estrogen receptor
- Growth rate
- Meningiomas
- Progesterone receptor
- Proliferating cell nuclear antigen
ASJC Scopus subject areas
- Surgery
- Clinical Neurology