RASAL2: Wrestling in the Combat of Ras Activation

Jia Shen; Yan Wang; Mien Chie Hung

doi:10.1016/j.ccr.2013.08.024

RASAL2: Wrestling in the Combat of Ras Activation

Jia Shen, Yan Wang, Mien Chie Hung

Molecular & Cellular Oncology

Research output: Contribution to journal › Short survey › peer-review

10 Scopus citations

Abstract

Oncogenic activation of Ras proteins due to missense mutations is frequently detected in human cancers but rarely in breast cancer. In this issue of Cancer Cell, McLaughlin and colleagues report that ablation of the GasGAP gene, RASAL2, is an alternative mechanism by which Ras becomes activated in breast cancer.

Original language	English (US)
Pages (from-to)	277-279
Number of pages	3
Journal	Cancer cell
Volume	24
Issue number	3
DOIs	https://doi.org/10.1016/j.ccr.2013.08.024
State	Published - Sep 9 2013

ASJC Scopus subject areas

Oncology
Cell Biology
Cancer Research

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10.1016/j.ccr.2013.08.024

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@article{c62ad7de89674aa898499d46b136dd4c,

title = "RASAL2: Wrestling in the Combat of Ras Activation",

abstract = "Oncogenic activation of Ras proteins due to missense mutations is frequently detected in human cancers but rarely in breast cancer. In this issue of Cancer Cell, McLaughlin and colleagues report that ablation of the GasGAP gene, RASAL2, is an alternative mechanism by which Ras becomes activated in breast cancer.",

author = "Jia Shen and Yan Wang and Hung, {Mien Chie}",

year = "2013",

month = sep,

day = "9",

doi = "10.1016/j.ccr.2013.08.024",

language = "English (US)",

volume = "24",

pages = "277--279",

journal = "Cancer cell",

issn = "1535-6108",

publisher = "Cell Press",

number = "3",

}

TY - JOUR

T1 - RASAL2

T2 - Wrestling in the Combat of Ras Activation

AU - Shen, Jia

AU - Wang, Yan

AU - Hung, Mien Chie

PY - 2013/9/9

Y1 - 2013/9/9

N2 - Oncogenic activation of Ras proteins due to missense mutations is frequently detected in human cancers but rarely in breast cancer. In this issue of Cancer Cell, McLaughlin and colleagues report that ablation of the GasGAP gene, RASAL2, is an alternative mechanism by which Ras becomes activated in breast cancer.

AB - Oncogenic activation of Ras proteins due to missense mutations is frequently detected in human cancers but rarely in breast cancer. In this issue of Cancer Cell, McLaughlin and colleagues report that ablation of the GasGAP gene, RASAL2, is an alternative mechanism by which Ras becomes activated in breast cancer.

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U2 - 10.1016/j.ccr.2013.08.024

DO - 10.1016/j.ccr.2013.08.024

M3 - Short survey

C2 - 24029223

AN - SCOPUS:84883613977

SN - 1535-6108

VL - 24

SP - 277

EP - 279

JO - Cancer cell

JF - Cancer cell

IS - 3

ER -

RASAL2: Wrestling in the Combat of Ras Activation

Abstract

ASJC Scopus subject areas

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