Abstract
Multidisciplinary efforts have defined a number of prognostic factors and newer strategies to improve the outcome of patients with breast cancer. Conservative surgery has led to improved functional and cosmetic results. The development of a number of effective adjuvant regimens has led to improved survival. In patients with stage I disease, several biological characteristics of tumor have been identified that are associated with increased risk of relapse. A multimodality approach to patients with locally advanced disease and inflammatory cancer has resulted in improved survival. A number of hormonal and cytotoxic drug contaminations can palliate metastatic disease, with a small fraction of patients remaining in extended remission. Dose-intensive programs may lead to further improvements in survival of selected patients with this disease.
Original language | English (US) |
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Pages (from-to) | 337-352 |
Number of pages | 16 |
Journal | American Journal of the Medical Sciences |
Volume | 301 |
Issue number | 5 |
DOIs | |
State | Published - 1991 |
Keywords
- Adjuvant treatment
- Breast cancer
- Chemotherapy
- Endocrine treatment
- Node-negative disease
ASJC Scopus subject areas
- General Medicine