Reconstruction of myocardial architecture at high resolution using diffusion tensor MRI

D. F. Scollan; A. Alexander Holmes; Jianyang Zhang; Raimond L. Winslow

Reconstruction of myocardial architecture at high resolution using diffusion tensor MRI

D. F. Scollan, A. Alexander Holmes, Jianyang Zhang, Raimond L. Winslow

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Diffusion tensor MRI (DTMRI) is a possible new means of elucidating the anatomic structure of the myocardium. It enjoys several advantages over traditional histological methods, including its ability to rapidly and nondestructively measure fiber architecture at very high resolution. However, quantitative validation of this MRI method has been lacking. Here, fiber orientations are estimated at the same locations using both DTMRI and histology in one formalin-fixed rabbit heart. Fiber orientations were statistically similar, differing on average by 5.3° (RMS) at any one location. The ventricular myofiber architecture of a number of normal rabbit hearts was then reconstructed using DTMRI into 3-D computer models for visualization. Myofiber organization appeared qualitatively similar to a previous high-resolution reconstruction using traditional histology.

Original language	English (US)
Title of host publication	Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Publisher	IEEE
Pages	1071
Number of pages	1
ISBN (Print)	0780356756
State	Published - 1999
Externally published	Yes
Event	Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) - Atlanta, GA, USA Duration: Oct 13 1999 → Oct 16 1999

Publication series

Name	Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume	2
ISSN (Print)	0589-1019

Other

Other	Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
City	Atlanta, GA, USA
Period	10/13/99 → 10/16/99

ASJC Scopus subject areas

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

Cite this

Scollan, D. F., Holmes, A. A., Zhang, J., & Winslow, R. L. (1999). Reconstruction of myocardial architecture at high resolution using diffusion tensor MRI. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (pp. 1071). (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; Vol. 2). IEEE.

Reconstruction of myocardial architecture at high resolution using diffusion tensor MRI. / Scollan, D. F.; Holmes, A. Alexander; Zhang, Jianyang et al.
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. IEEE, 1999. p. 1071 (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; Vol. 2).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Scollan, DF, Holmes, AA, Zhang, J & Winslow, RL 1999, Reconstruction of myocardial architecture at high resolution using diffusion tensor MRI. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, vol. 2, IEEE, pp. 1071, Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS), Atlanta, GA, USA, 10/13/99.

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title = "Reconstruction of myocardial architecture at high resolution using diffusion tensor MRI",

abstract = "Diffusion tensor MRI (DTMRI) is a possible new means of elucidating the anatomic structure of the myocardium. It enjoys several advantages over traditional histological methods, including its ability to rapidly and nondestructively measure fiber architecture at very high resolution. However, quantitative validation of this MRI method has been lacking. Here, fiber orientations are estimated at the same locations using both DTMRI and histology in one formalin-fixed rabbit heart. Fiber orientations were statistically similar, differing on average by 5.3° (RMS) at any one location. The ventricular myofiber architecture of a number of normal rabbit hearts was then reconstructed using DTMRI into 3-D computer models for visualization. Myofiber organization appeared qualitatively similar to a previous high-resolution reconstruction using traditional histology.",

author = "Scollan, {D. F.} and Holmes, {A. Alexander} and Jianyang Zhang and Winslow, {Raimond L.}",

note = "Copyright: Copyright 2004 Elsevier Science B.V., Amsterdam. All rights reserved.; Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) ; Conference date: 13-10-1999 Through 16-10-1999",

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AU - Scollan, D. F.

AU - Holmes, A. Alexander

AU - Zhang, Jianyang

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N2 - Diffusion tensor MRI (DTMRI) is a possible new means of elucidating the anatomic structure of the myocardium. It enjoys several advantages over traditional histological methods, including its ability to rapidly and nondestructively measure fiber architecture at very high resolution. However, quantitative validation of this MRI method has been lacking. Here, fiber orientations are estimated at the same locations using both DTMRI and histology in one formalin-fixed rabbit heart. Fiber orientations were statistically similar, differing on average by 5.3° (RMS) at any one location. The ventricular myofiber architecture of a number of normal rabbit hearts was then reconstructed using DTMRI into 3-D computer models for visualization. Myofiber organization appeared qualitatively similar to a previous high-resolution reconstruction using traditional histology.

AB - Diffusion tensor MRI (DTMRI) is a possible new means of elucidating the anatomic structure of the myocardium. It enjoys several advantages over traditional histological methods, including its ability to rapidly and nondestructively measure fiber architecture at very high resolution. However, quantitative validation of this MRI method has been lacking. Here, fiber orientations are estimated at the same locations using both DTMRI and histology in one formalin-fixed rabbit heart. Fiber orientations were statistically similar, differing on average by 5.3° (RMS) at any one location. The ventricular myofiber architecture of a number of normal rabbit hearts was then reconstructed using DTMRI into 3-D computer models for visualization. Myofiber organization appeared qualitatively similar to a previous high-resolution reconstruction using traditional histology.

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Reconstruction of myocardial architecture at high resolution using diffusion tensor MRI

Abstract

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ASJC Scopus subject areas

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