Regression of an enchondroma: a case report and proposed etiology

Anirban Sensarma; John E. Madewell; Jeanne M. Meis; Rajendra Kumar; Patrick P. Lin; Behrang Amini

doi:10.1007/s00256-014-2032-1

Regression of an enchondroma: a case report and proposed etiology

Anirban Sensarma, John E. Madewell, Jeanne M. Meis, Rajendra Kumar, Patrick P. Lin, Behrang Amini

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Enchondromas are common benign bone lesions that are found in the medullary cavity of tubular bones, usually at the metaphysis. Regression is highly unusual, and loss of matrix mineralization in an existing enchondroma should prompt investigation for malignant transformation. We present the case of a 50-year-old woman with an enchondroma of the proximal humeral metadiaphysis, which underwent loss of matrix mineralization that corresponded to replacement with marrow fat on MRI. This transformation of the cartilage tumor matrix into normal bone marrow may occur in a process similar to that seen with endochondral ossification.

Original language	English (US)
Pages (from-to)	739-742
Number of pages	4
Journal	Skeletal radiology
Volume	44
Issue number	5
DOIs	https://doi.org/10.1007/s00256-014-2032-1
State	Published - Mar 18 2015

Keywords

Enchondroma
MRI
Radiography
Regression

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1007/s00256-014-2032-1

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abstract = "Enchondromas are common benign bone lesions that are found in the medullary cavity of tubular bones, usually at the metaphysis. Regression is highly unusual, and loss of matrix mineralization in an existing enchondroma should prompt investigation for malignant transformation. We present the case of a 50-year-old woman with an enchondroma of the proximal humeral metadiaphysis, which underwent loss of matrix mineralization that corresponded to replacement with marrow fat on MRI. This transformation of the cartilage tumor matrix into normal bone marrow may occur in a process similar to that seen with endochondral ossification.",

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T2 - a case report and proposed etiology

AU - Sensarma, Anirban

AU - Madewell, John E.

AU - Meis, Jeanne M.

AU - Kumar, Rajendra

AU - Lin, Patrick P.

AU - Amini, Behrang

PY - 2015/3/18

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N2 - Enchondromas are common benign bone lesions that are found in the medullary cavity of tubular bones, usually at the metaphysis. Regression is highly unusual, and loss of matrix mineralization in an existing enchondroma should prompt investigation for malignant transformation. We present the case of a 50-year-old woman with an enchondroma of the proximal humeral metadiaphysis, which underwent loss of matrix mineralization that corresponded to replacement with marrow fat on MRI. This transformation of the cartilage tumor matrix into normal bone marrow may occur in a process similar to that seen with endochondral ossification.

AB - Enchondromas are common benign bone lesions that are found in the medullary cavity of tubular bones, usually at the metaphysis. Regression is highly unusual, and loss of matrix mineralization in an existing enchondroma should prompt investigation for malignant transformation. We present the case of a 50-year-old woman with an enchondroma of the proximal humeral metadiaphysis, which underwent loss of matrix mineralization that corresponded to replacement with marrow fat on MRI. This transformation of the cartilage tumor matrix into normal bone marrow may occur in a process similar to that seen with endochondral ossification.

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KW - MRI

KW - Radiography

KW - Regression

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Regression of an enchondroma: a case report and proposed etiology

Abstract

Keywords

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