@article{f835c6ce53174e6691319a0bdc849670,
title = "Remote physiological monitoring of acute cocaine exposure",
abstract = "Cocaine exposure results in predictable cardiovascular changes. The current study evaluated the utility of BioHarness for assessing cardiovascular and respiratory changes following cocaine exposure (0 and 40 mg, IV) under controlled laboratory conditions. Participants (n = 28) included non-treatment-seeking, cocaine-dependent volunteers. Results showed that BioHarness was able to detect a significant increase in heart rate following cocaine exposure, in comparison to placebo, (p < 0.0001). Additionally, heart rate values obtained using BioHarness were significantly correlated with those obtained from standard hospital equipment (p < 0.001). Significantly greater peak effects in breathing rate were also observed (p = 0.04). BioHarness is a promising remote physiological monitoring device that can accurately assess exposure to cocaine in the laboratory and may provide additional advantages when compared to standard hospital equipment.",
keywords = "BioHarness, Cardiovascular, Cocaine, Remote physiological monitoring, Respiration",
author = "Yoon, {Jin H.} and Shah, {Ravi S.} and Arnoudse, {Nicholas M.} and {De La Garza}, Richard",
note = "Funding Information: Grant funding was provided by the National Institute on Drug Abuse to Dr De La Garza (DA023624, DA023624-03S1). This material is the result of work supported with resources and the use of facilities at Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX. The current study was approved by the Baylor College of Medicine and Michael E. Debakey Veterans Affairs Medical Center Bioethical Committees. All participants provided informed consent and the study was conducted in accordance with the Declaration of Helsinkii. Jin Yoon developed the study design, conducted data analysis, and wrote the initial full draft of the manuscript. Richard De La Garza provided guidance during the course of the study a extensive feedback on the manuscript, and helped with the final data analysis which was incorporated into the final version. Ravi Shah and Nicholas Arnoudse were critical in conducting study-related procedures and assisted in data analyses. All authors read and provided comments and suggestions for the final version of the manuscript. The authors report no conflicts of interest.",
year = "2014",
month = jul,
doi = "10.3109/03091902.2014.902513",
language = "English (US)",
volume = "38",
pages = "244--250",
journal = "Journal of Medical Engineering and Technology",
issn = "0309-1902",
publisher = "Informa Healthcare",
number = "5",
}