Renal cell carcinoma with osteoclast-like giant cells

Adel K. El-Naggar; Khalid Gaber; Nelson G. Ordonez

doi:10.1007/BF01605464

Renal cell carcinoma with osteoclast-like giant cells

Adel K. El-Naggar, Khalid Gaber, Nelson G. Ordonez

Pathology, Anatomical

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Primary extraskeletal epithelial neoplasms with osteoclast-like giant cells are rare. We describe a case of renal cell carcinoma with a sarcomatoid component and non-neoplastic osteoclast-like giant cells. The giant cells were noted in both the conventional and the sarcomatoid components of the neoplasm. Immunohistochemical studies indicate that these cells are monocyte/histiocyte in origin and most probably a host stromal reaction to the neoplasm.

Original language	English (US)
Pages (from-to)	427-431
Number of pages	5
Journal	Virchows Archiv A Pathological Anatomy and Histopathology
Volume	422
Issue number	5
DOIs	https://doi.org/10.1007/BF01605464
State	Published - Sep 1993

Keywords

Multinucleated giant cell
Osteoclast-like giant cell
Renal cell carcinoma
Renal cell neoplasms

ASJC Scopus subject areas

Pathology and Forensic Medicine

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10.1007/BF01605464

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title = "Renal cell carcinoma with osteoclast-like giant cells",

abstract = "Primary extraskeletal epithelial neoplasms with osteoclast-like giant cells are rare. We describe a case of renal cell carcinoma with a sarcomatoid component and non-neoplastic osteoclast-like giant cells. The giant cells were noted in both the conventional and the sarcomatoid components of the neoplasm. Immunohistochemical studies indicate that these cells are monocyte/histiocyte in origin and most probably a host stromal reaction to the neoplasm.",

keywords = "Multinucleated giant cell, Osteoclast-like giant cell, Renal cell carcinoma, Renal cell neoplasms",

author = "El-Naggar, {Adel K.} and Khalid Gaber and Ordonez, {Nelson G.}",

year = "1993",

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AU - El-Naggar, Adel K.

AU - Gaber, Khalid

AU - Ordonez, Nelson G.

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N2 - Primary extraskeletal epithelial neoplasms with osteoclast-like giant cells are rare. We describe a case of renal cell carcinoma with a sarcomatoid component and non-neoplastic osteoclast-like giant cells. The giant cells were noted in both the conventional and the sarcomatoid components of the neoplasm. Immunohistochemical studies indicate that these cells are monocyte/histiocyte in origin and most probably a host stromal reaction to the neoplasm.

AB - Primary extraskeletal epithelial neoplasms with osteoclast-like giant cells are rare. We describe a case of renal cell carcinoma with a sarcomatoid component and non-neoplastic osteoclast-like giant cells. The giant cells were noted in both the conventional and the sarcomatoid components of the neoplasm. Immunohistochemical studies indicate that these cells are monocyte/histiocyte in origin and most probably a host stromal reaction to the neoplasm.

KW - Multinucleated giant cell

KW - Osteoclast-like giant cell

KW - Renal cell carcinoma

KW - Renal cell neoplasms

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Renal cell carcinoma with osteoclast-like giant cells

Abstract

Keywords

ASJC Scopus subject areas

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