TY - JOUR
T1 - Repeated filling of elastomeric infuser pumps for home-based subcutaneous medications
T2 - A case series
AU - Julião, Miguel
AU - Sobral, Maria Ana
AU - Runa, Daniela
AU - Calçada, Paula
AU - Calaveiras, Patrícia
AU - Chaves, Petra
AU - Gonçalves, Célia
AU - de Sousa, Paulo Faria
AU - Bruera, Eduardo
N1 - Publisher Copyright:
© 2021 MA Healthcare Ltd. All rights reserved.
PY - 2021/4/2
Y1 - 2021/4/2
N2 - Background: Several medical devices have been developed for continuous subcutaneous drug infusion for home palliative care (HPC), such as elastomeric infuser pumps (EIP). There is no evidence on the repeated filling of EIP for continuous subcutaneous delivery for HPC. Aim: A clinical case series report of terminally-ill patients cared for in HPC, with repeated filling of EIPs for home-based subcutaneous medications. Methods: A retrospective analysis of each patient´s EIP-related entries in an anonymised database regarding: 1) EIP general functioning aspects; 2) clinical aspects: symptom control and local skin complications. Overall and per-patient cost-saving was also calculated. Findings: A total of 10 cases were analysed (four 50-hour EIP and six 30-hour EIP). All EIPs had a mean number of refillings (standard deviation (SD), mode) of 1.6 ((0.5), 2); with 3.2 drugs on average used in each EIP ((1.4), 4).Approximate total mean (SD) usage time for both types of EIP was 87 (29) hours; and all EIP were used, on average (SD), 49 (23) hours more than its labelled duration. All EIPs showed a complete reservoir deflation between refilling. Only one patient had a minor skin complication and no symptom aggravation was observed, except for two cases with mild anxiety and agitation. Cost-saving analysis for the complete case series showed that EIP refillings saved, on average, €24 per-patient and a total of nearly €240, for both types of infuser pumps. Conclusion: This preliminary study suggests that refilling is safe and reduces cost. Future research on EIP refilling using controlled and systematic methodologies are warranted.
AB - Background: Several medical devices have been developed for continuous subcutaneous drug infusion for home palliative care (HPC), such as elastomeric infuser pumps (EIP). There is no evidence on the repeated filling of EIP for continuous subcutaneous delivery for HPC. Aim: A clinical case series report of terminally-ill patients cared for in HPC, with repeated filling of EIPs for home-based subcutaneous medications. Methods: A retrospective analysis of each patient´s EIP-related entries in an anonymised database regarding: 1) EIP general functioning aspects; 2) clinical aspects: symptom control and local skin complications. Overall and per-patient cost-saving was also calculated. Findings: A total of 10 cases were analysed (four 50-hour EIP and six 30-hour EIP). All EIPs had a mean number of refillings (standard deviation (SD), mode) of 1.6 ((0.5), 2); with 3.2 drugs on average used in each EIP ((1.4), 4).Approximate total mean (SD) usage time for both types of EIP was 87 (29) hours; and all EIP were used, on average (SD), 49 (23) hours more than its labelled duration. All EIPs showed a complete reservoir deflation between refilling. Only one patient had a minor skin complication and no symptom aggravation was observed, except for two cases with mild anxiety and agitation. Cost-saving analysis for the complete case series showed that EIP refillings saved, on average, €24 per-patient and a total of nearly €240, for both types of infuser pumps. Conclusion: This preliminary study suggests that refilling is safe and reduces cost. Future research on EIP refilling using controlled and systematic methodologies are warranted.
KW - Clinical case series report
KW - Continuous
KW - Elastomeric infuser pump
KW - Home-based palliative care
KW - Repeated filling
KW - Subcutaneous infusion
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M3 - Article
C2 - 33886356
AN - SCOPUS:85104876048
SN - 1357-6321
VL - 27
SP - 107
EP - 115
JO - International Journal of Palliative Nursing
JF - International Journal of Palliative Nursing
IS - 2
ER -