@article{b8e779431c2046919232edacce64adaf,
title = "Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue",
abstract = "Solid tumors are under-sampled in the clinic, such that only 0.0005% of initial tumor volume is used as input for diagnostic testing. Litchfield et al. apply the principles of representative sampling to implement an unbiased tumor sampling approach that improves the reproducibility and accuracy of next-generation sequencing.",
keywords = "biomarkers, homogenization, molecular profiling, representative sampling, tumor hetereogeneity, tumor mutational burden, tumor sampling, tumor sequencing",
author = "{PEACE Consortium} and Kevin Litchfield and Stacey Stanislaw and Lavinia Spain and Gallegos, {Lisa L.} and Andrew Rowan and Desiree Schnidrig and Heidi Rosenbaum and Alexandre Harle and Lewis Au and Hill, {Samantha M.} and Zayd Tippu and Jennifer Thomas and Lisa Thompson and Hang Xu and Stuart Horswell and Aoune Barhoumi and Carol Jones and Leith, {Katherine F.} and Burgess, {Daniel L.} and Watkins, {Thomas B.K.} and Emilia Lim and Birkbak, {Nicolai J.} and Philippe Lamy and Iver Nordentoft and Lars Dyrskj{\o}t and Lisa Pickering and Stephen Hazell and Mariam Jamal-Hanjani and Chris Abbosh and Shiu, {Kai Keen} and John Bridgewater and Daniel Hochhauser and Martin Forster and Lee, {Siow Ming} and Tanya Ahmad and Dionysis Papadatos-Pastos and Sam Janes and {Van Loo}, Peter and Katey Enfield and Nicholas McGranahan and Ariana Huebner and Sergio Quezada and Stephan Beck and Peter Parker and Henning Walczak and Tariq Enver and Rob Hynds and Mary Falzon and Ian Proctor and Ron Sinclair",
note = "Publisher Copyright: {\textcopyright} 2020 The Authors",
year = "2020",
month = may,
day = "5",
doi = "10.1016/j.celrep.2020.107550",
language = "English (US)",
volume = "31",
journal = "Cell Reports",
issn = "2211-1247",
publisher = "Cell Press",
number = "5",
}