Reproductive and Hormonal Considerations in Women at Increased Risk for Hereditary Gynecologic Cancers: Society of Gynecologic Oncology and American Society for Reproductive Medicine Evidence-Based Review: Hereditary gynecologic cancers and fertility

Lee may Chen, Stephanie V. Blank, Elizabeth Burton, Karen Glass, Elizabeth Penick, Terri Woodard

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

Providers who care for women at risk for hereditary gynecologic cancers must consider the impact of these conditions on reproductive and hormonal health. This document reviews potential options for cancer prevention, family building, genetic testing and management of surgical menopause in this patient population. Capsule: Women predisposed to hereditary gynecologic cancer have options for fertility preservation, preimplantation genetic testing to select embryos without pathogenic variants, pregnancy through gestational carriers after hysterectomy and hormone replacement.

Original languageEnglish (US)
Pages (from-to)508-514
Number of pages7
JournalGynecologic oncology
Volume155
Issue number3
DOIs
StatePublished - Dec 2019

Keywords

  • Endometrial cancer
  • Genetic counseling
  • Menopause and hormone replacement therapy
  • Ovarian cancer
  • Quality of life issues

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology

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