Research advances on bladder cancer associated genes

Rui Zhang, Jian Jun Zhang, Zu Gen He, Shu Jun Cheng, Yan Ning Gao

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

Bladder cancer is the most common urinary tumors in China. Carcinogenesis of bladder is a multistep process. Accumulation of abnormal genotypes in a long period leads to malignant phenotypes. The genes associated with bladder carcinogenesis include oncogenes (such as H-ras, FGFR3, erbB2, CCND1, mdm2), tumor suppressor genes (such as INK4A/ARF, Rb, TP53, PTEN, TSC1, PTCH, DBCCR1), and DNA mismatch repair genes, etc. In this review, the authors discussed the recent research advances on the genes associated with bladder carcinoma.

Original languageEnglish (US)
Pages (from-to)104-107
Number of pages4
JournalAi zheng = Aizheng = Chinese journal of cancer
Volume22
Issue number1
StatePublished - Jan 2003

ASJC Scopus subject areas

  • Oncology

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