Response of jejunal mucosa to fractionated doses of neutrons or γ-rays

H. R. Withers; A. M. Chu; K. A. Mason; B. O. Reid; H. T. Barkley; J. B. Smathers

doi:10.1016/0014-2964(74)90183-2

Response of jejunal mucosa to fractionated doses of neutrons or γ-rays

H. R. Withers, A. M. Chu, K. A. Mason, B. O. Reid, H. T. Barkley, J. B. Smathers

Experimental Radiation Oncology

Research output: Contribution to journal › Article › peer-review

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Abstract

The RBE_n + γ/γ of fast neutrons produced by the ⁹Be(d,n) 9B reaction (E_d = 50 MeV) relative to ⁶⁰Co γ-rays for killing of jejunal crypt stem cells has been measured over a wide range of doses beginning at 400 rad of γ-rays, and extending to doses as high as 1600 rad. Dose-equivalent values for recovery as a function of the size of the dose-per-fraction have been measured. When γ-ray doses up to about 400 rad are given, about 60% of the dose is "recovered". With neutron doses of 100-200 rad, the recovered dose amounts to only about 13% of the given dose.

Original language	English (US)
Pages (from-to)	249-252
Number of pages	4
Journal	European Journal of Cancer (1965)
Volume	10
Issue number	4
DOIs	https://doi.org/10.1016/0014-2964(74)90183-2
State	Published - Apr 1974

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General Medicine

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10.1016/0014-2964(74)90183-2

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@article{c216e35452484246aa7939d3802c081c,

title = "Response of jejunal mucosa to fractionated doses of neutrons or γ-rays",

abstract = "The RBEn + γ/γ of fast neutrons produced by the 9Be(d,n) 9B reaction (Ed = 50 MeV) relative to 60Co γ-rays for killing of jejunal crypt stem cells has been measured over a wide range of doses beginning at 400 rad of γ-rays, and extending to doses as high as 1600 rad. Dose-equivalent values for recovery as a function of the size of the dose-per-fraction have been measured. When γ-ray doses up to about 400 rad are given, about 60% of the dose is {"}recovered{"}. With neutron doses of 100-200 rad, the recovered dose amounts to only about 13% of the given dose.",

author = "Withers, {H. R.} and Chu, {A. M.} and Mason, {K. A.} and Reid, {B. O.} and Barkley, {H. T.} and Smathers, {J. B.}",

note = "Funding Information: *This investigation was supported by NIH Research Grants CA12542, CA 11138-05 and CA06294-12 from the National Cancer Institute. ~'Present address: Dept. of Radiation Medicine, Massachusetts General Hospital, Boston, Mass., U.S.A.",

year = "1974",

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doi = "10.1016/0014-2964(74)90183-2",

language = "English (US)",

volume = "10",

pages = "249--252",

journal = "European Journal of Cancer (1965)",

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publisher = "Pergamon Press Ltd.",

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TY - JOUR

T1 - Response of jejunal mucosa to fractionated doses of neutrons or γ-rays

AU - Withers, H. R.

AU - Chu, A. M.

AU - Mason, K. A.

AU - Reid, B. O.

AU - Barkley, H. T.

AU - Smathers, J. B.

N1 - Funding Information: *This investigation was supported by NIH Research Grants CA12542, CA 11138-05 and CA06294-12 from the National Cancer Institute. ~'Present address: Dept. of Radiation Medicine, Massachusetts General Hospital, Boston, Mass., U.S.A.

PY - 1974/4

Y1 - 1974/4

N2 - The RBEn + γ/γ of fast neutrons produced by the 9Be(d,n) 9B reaction (Ed = 50 MeV) relative to 60Co γ-rays for killing of jejunal crypt stem cells has been measured over a wide range of doses beginning at 400 rad of γ-rays, and extending to doses as high as 1600 rad. Dose-equivalent values for recovery as a function of the size of the dose-per-fraction have been measured. When γ-ray doses up to about 400 rad are given, about 60% of the dose is "recovered". With neutron doses of 100-200 rad, the recovered dose amounts to only about 13% of the given dose.

AB - The RBEn + γ/γ of fast neutrons produced by the 9Be(d,n) 9B reaction (Ed = 50 MeV) relative to 60Co γ-rays for killing of jejunal crypt stem cells has been measured over a wide range of doses beginning at 400 rad of γ-rays, and extending to doses as high as 1600 rad. Dose-equivalent values for recovery as a function of the size of the dose-per-fraction have been measured. When γ-ray doses up to about 400 rad are given, about 60% of the dose is "recovered". With neutron doses of 100-200 rad, the recovered dose amounts to only about 13% of the given dose.

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JO - European Journal of Cancer (1965)

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IS - 4

ER -

Response of jejunal mucosa to fractionated doses of neutrons or γ-rays

Abstract

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